[KSCI] Korea Science Citation Index Service

Immunoregulation Effect of KamiBohuh-tang

Park Kyung Mi (Department of Gynecology, College of Oriental Medicine, DaeJeon University)
Jung Jin Hong (Department of Gynecology, College of Oriental Medicine, DaeJeon University)
Yoo Dong Youl (Department of Gynecology, College of Oriental Medicine, DaeJeon University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.16, no.1, 2002 , pp. 186-191 More about this Journal

Abstract

The purpose of this study is to prove the efficacy of KamiBohuh-tang(KBT) on immunoregulation and the possibility of KBT as an immunoadjuvant. KBT with solid feed was administered orally once a day for 7 days to an experimental group, a solution of salt and solid feed without KBT to a control group. After a week T cell, B cell, cytokines, nitric oxide and phagocytic activity are measured. KBT enhanced the proliferation of splenocytes and the subpopulation of Th cells in splenic T-Iymphocytes, but did not affect the proliferation of thymocytes. KBT decreased the subpopulation of T-Iymphocytes in splenocytes. KBT enhanced the production of interferon-γ. interleukin-2, interleukin-4 in mice serum and the phagocytic activity in peritoneal macrophages but it suppressed the production of nitric oxide. These results suggest that KBT is a potent prescription on immune response via the increase of the proliferation of splenocytes, the production of cytokines from splenic Th cells and the phagocytic activity in vivo.

Keywords

KamiBohuh-tang; splenocytes; thymocytes; nitric oxide; phagocytic activity; cytokines;

Citations & Related Records

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