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http://dx.doi.org/10.14253/acn.2022.24.2.73

Abnormal spontaneous electromyographic activity in myasthenia gravis causing a diagnostic confusion: a case report and literature review  

Kim, Sohyeon (Department of Neurology, Dongsan Hospital, Keimyung University School of Medicine)
Kang, Minsung (Department of Neurology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University)
Park, Jin-Sung (Department of Neurology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University)
Seok, Hung Youl (Department of Neurology, Dongsan Hospital, Keimyung University School of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.24, no.2, 2022 , pp. 73-78 More about this Journal
Abstract
Some cases of myasthenia gravis (MG) with abnormal spontaneous activity (ASA) in needle electromyography (EMG) have been reported, but the associated clinical characteristics remain to be fully elucidated. We report the case of a 36-year-old male with MG in whom ASA was observed. This study highlights that ASA may appear in needle EMG in patients with severe MG who predominantly have bulbar and/or respiratory involvement. Care is needed because this often accompanies myopathic features and can be misdiagnosed as myopathy.
Keywords
Myasthenia gravis; Electromyography; Spontaneous activity;
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1 Kannaditharayil D, Napier F, Granit V, Bieri P, Herskovitz S. Abnormal spontaneous activity on needle electromyography in myasthenia gravis. Muscle Nerve 2017;56:E11-E12.   DOI
2 Musser WS, Barbano RL, Thornton CA, Moxley RT 3rd, Herrmann DN, Logigian EL. Distal myasthenia gravis with a decrement, an increment, and denervation. J Clin Neuromuscul Dis 2001;3:16-19.   DOI
3 Fearon C, Mullins G, Reid V, Smyth S. Distal myasthenia gravis presenting as isolated distal myopathy. Muscle Nerve 2015;52:308-309.   DOI
4 Tsironis T, Catania S. Reversible spontaneous EMG activity during myasthenic crisis: two case reports. eNeurologicalSci 2019;14:16-18.   DOI
5 Asan F, Tutuncu M, Gunduz A, Adatepe NU. Tongue atrophy and myopathy mimicking EMG findings in a case with acethylcholine receptor-positive myasthenia gravis. Cerrahpa-a Med J 2022;46:75-77.
6 Maher J, Grand'Maison F, Nicolle MW, Strong MJ, Bolton CF. Diagnostic difficulties in myasthenia gravis. Muscle Nerve 1998; 21:577-583.   DOI
7 Samuraki M, Furui E, Komai K, Takamori M, Yamada M. Myasthenia gravis presenting with unusual neurogenic muscle atrophy. Muscle Nerve 2007;36:394-399.   DOI
8 Shah PA, Wadia PM. Reversible man-in-the-barrel syndrome in myasthenia gravis. Ann Indian Acad Neurol 2016;19:99-101.   DOI
9 Sanders DB, El-Salem K, Massey JM, McConville J, Vincent A. Clinical aspects of MuSK antibody positive seronegative MG. Neurology 2003;60:1978-1980.   DOI
10 Pelzer EA, Galldiks N, Brunn A, Fink GR, Haupt WF. Evidence of spontaneous activity in two cases of severe myasthenia gravis. J Neurol Neurophysiol 2012;3:136.