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http://dx.doi.org/10.14253/acn.2022.24.1.26

Lumbosacral polyradiculoneuropathy associated with combination therapy of nivolumab and ipilimumab  

Cho, Eun Bin (Department of Neurology, Gyeongsang National University Changwon Hospital)
Kim, Seung Joo (Department of Neurology, Gyeongsang National University Changwon Hospital)
Yang, Tae-Won (Department of Neurology, Gyeongsang National University Changwon Hospital)
Jung, Seunguk (Department of Neurology, Gyeongsang National University Changwon Hospital)
Jeong, Heejeong (Department of Neurology, Gyeongsang National University Changwon Hospital)
Park, Ki-Jong (Department of Neurology, Gyeongsang National University Changwon Hospital)
Publication Information
Annals of Clinical Neurophysiology / v.24, no.1, 2022 , pp. 26-29 More about this Journal
Abstract
Immune checkpoint inhibitors (ICIs) have emerged as one of the most promising therapeutic options for advanced cancers. While ICIs have improved survival in multiple cancers, their increased use is restricted by various immune-related adverse events. In this report we describe a patient with renal cell carcinoma who received a combination of ICIs, nivolumab plus ipilimumab, and who developed lumbosacral polyradiculoneuropathy. Corticosteroid use was an effective treatment for this patient.
Keywords
Polyradiculoneuropathy; Drug-related side effects; Immune checkpoint inhibitors;
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