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http://dx.doi.org/10.14253/acn.2022.24.1.1

Quantitative sudomotor axon reflex test (QSART) as a diagnostic tool of small fiber neuropathy  

Suh, Bum Chun (Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.24, no.1, 2022 , pp. 1-6 More about this Journal
Abstract
Small fiber neuropathy is a painful neuropathy that cannot be assessed using nerve conduction studies. A skin biopsy and quantitative sensory testing (QST) are the gold standards for small fiber neuropathy diagnosis. However, a skin biopsy is invasive and commercially unavailable in Korea. QST is a method involving a thermal threshold, but its results can be affected by cognition as well as lesions of the central nervous system. Quantitative sudomotor axon reflex test (QSART) is a quantitative method of assessing sweat glands innervated by small fibers. In this review, we assessed the utility of QSART in evaluating small fiber neuropathy.
Keywords
Small fiber neuropathy; Sweat; Autonomic fibers; Quantitative sudomotor axon reflex test; Quantitative sensory testing;
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