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http://dx.doi.org/10.14253/acn.2020.22.1.41

Steroid-resistant sarcoid myositis that was successfully treated with oral methotrexate  

Noh, Kyung-Ha (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital)
Huh, So-Young (Department of Neurology, Kosin University College of Medicine)
Park, Young-Eun (Department of Neurology, Pusan National University Hospital)
Shin, Jin-Hong (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital)
Kim, Dae-Seong (Department of Neurology, Research Institute for Convergence of Biomedical Research, Pusan National University Yangsan Hospital)
Publication Information
Annals of Clinical Neurophysiology / v.22, no.1, 2020 , pp. 41-45 More about this Journal
Abstract
Acute sarcoid myositis is rarely complicated by sarcoidosis, and steroid therapy is considered the standard treatment. We experienced a patient with acute sarcoid myositis who did not respond to aggressive high-dose corticosteroid therapy, but showed a dramatic improvement after the addition of weekly low-dose oral methotrexate (MTX). This intervention allowed the resumption of normal daily activities after 6 months. Our case strongly suggests that MTX should be considered in patients with acute sarcoid myositis that is resistant to corticosteroid therapy.
Keywords
Sarcoidosis; Myositis; Corticosteroid; Methotrexate;
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