Browse > Article
http://dx.doi.org/10.14253/kjcn.2014.16.1.27

A Case of Wernicke's Encephalopathy Presenting as Acute Bilateral Wrist Drop  

Kim, Do-Hyung (Biomedical Research Institute of Chonbuk National University Hospital)
Oh, Sun-Young (Department of Neurology, Chonbuk National University College of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.16, no.1, 2014 , pp. 27-31 More about this Journal
Abstract
Thiamine deficiency can cause peripheral polyneuropathy and Wernicke's encephalopathy. Wernicke's encephalopathy is characterized by ataxia, ophthalmoplegia, nystagmus, and confusion, and typically presents acute and rapidly progressive course, whereas peripheral neuropathy associated with thiamine deficiency manifests chronic and slowly progressive one. However, acute and rapidly progressive axonal polyneuropathy combined with Wernicke's encephalopathy is quite rare and unusual. Here, we describe a patient with Wernicke's encephalopathy who presented with acute bilateral axonal neuropathy.
Keywords
Wernicke's encephalopathy; Acute axonal polyneuropathy; Thiamine;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Thomson AD, Guerrini I, Marshall EJ. Wernicke's encephalopathy: role of thiamine. Practical Gastroenterol 2009;75:21-30.
2 Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med 2007;50:715-721.   DOI   ScienceOn
3 Butterworth RF. Thiamin deficiency and brain disorders. Nutr. Res. Rev. 2003;16:277-283.
4 Lehmann HC, Lindenberg R, Arendt G, Ploner M. Acute axonal neuropathy and Wernicke's encephalopathy. J Neurol 2006; 253:1516-1517.   DOI
5 Koike H, Misu K, Hattori N, Ito S, Ichimura M, Ito H, et al. Postgastrectomy polyneuropathy with thiamine deficiency. J Neurol Neurosurg Psychiatry 2001;71:357-362.   DOI
6 Zuccoli G, Pipitone N. Neuroimaging findings in acute Wernicke's encephalopathy: review of the literature. AJR Am J Roentgenol 2009;192:501-508.   DOI   ScienceOn
7 Ishibashi S, Yokota T, Shiojiri T, Matunaga T, Tanaka H, Nishina K, et al. Reversible acute axonal polyneuropathy associated with Wernicke-Korsakoff syndrome: impaired physiological nerve conduction due to thiamine deficiency? J Neurol Neurosurg Psychiatry 2003;74:674-676.   DOI   ScienceOn
8 Thaisetthawatkul P, Collazo-Clavell ML, Sarr MG, Norell JE, Dyck PJ. A controlled study of peripheral neuropathy after bariatric surgery. Neurology 2004;63:1462-1470.   DOI   ScienceOn
9 Galvin R, Bråthen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol 2010;17:1408-1418.   DOI   ScienceOn