Browse > Article

Multiple Cranial Neuropathy with and Polyradiculoneuropathy as a Delayed Sequelae after of Ethylene Glycol Intoxication  

Kim, Min-Soo (Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine)
Kim, Sun-Young (Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine)
Kwon, Jee-Hyun (Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine)
Kim, Wook-Joo (Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine)
Jung, Hyun-Chul (Department of Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.15, no.2, 2013 , pp. 63-67 More about this Journal
Abstract
Multiple cranial and peripheral neuropathies as a delayed sequellae of ethylene glycol poisoning is a less well known clinical entity and its information about long-term electrophysiological and clinical outcomes is limited. We report a 45-year-old male who presented with acute renal failure and subsequently developed multiple cranial neuropathy, respiratory failure, and flaccid tetraparesis. Through sequential electrophysiological studies, we would like suggest that the main pathophysiology of ethylene glycol-related neuropathy is a demyelinating polyradiculoneuropathy with secondary axonal degeneration.
Keywords
Ethylene glycol; Multiple cranial neuropathy; Polyneuropathy;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Pellegrino B, Parravani A, Cook L, Mackay K. Ethylene glycol intoxication: Disparate findings of immediate versus delayed presentation. W V Med J 2006;102:32-34.
2 Zhou L, Zabad R, Lewis RA. Ethylene glycol intoxication: electrophysiological studies suggest a polyradiculopathy. Neurology 2002;59:1809-1810.   DOI   ScienceOn
3 Lewis LD, Smith BW, Mamourian AC. Delayed sequelae after acute overdoses or poisonings: cranial neuropathy related to ethylene glycol ingestion. Clin Pharmacol Ther 1997;61:692-699.   DOI
4 Hasbani MJ, Sansing LH, Perrone J, Asbury AK, Bird SJ. Encephalopathy and peripheral neuropathy following diethylene glycol ingestion. Neurology 2005;64:1273-1275.   DOI   ScienceOn
5 Alzouebi M, Sarrigiannis PG, Hadjivassiliou M. Acute polyradiculoneuropathy with renal failure: mind the anion gap. J Neurol Neurosurg Psychiatry 2008;79:842-844.   DOI   ScienceOn
6 Tobe TJ, Braam GB, Meulenbelt J, van Dijk GW. Ethylene glycol poisoning mimicking Snow White. Lancet 2002;359: 444-445.
7 Barceloux DG, Krenzelok EP, Olson K, Watson W. American academy of clinical toxicology practice guidelines on the treatment of ethylene glycol poisoning. Ad Hoc Committee. J Toxicol Clin Toxicol 1999;37:537-560.   DOI   ScienceOn
8 Froberg K, Dorion RP, McMartin KE. The role of calcium oxalate crystal deposition in cerebral vessels during ethylene glycol poisoning. Clin Toxicol (Phila) 2006;44:315-318.   DOI   ScienceOn
9 Le Quesne PM. Electrophysiological investigation of toxic neuropathies. Acta Neurol Scand Suppl 1982;92:75-87.
10 Baldwin F, Sran H. Delayed ethylene glycol poisoning presenting with abdominal pain and multiple cranial and peripheral neuropathies: a case report. J Med Case Reports 2010;4:220.   DOI   ScienceOn