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Nephrogenic Systemic Fibrosis with Myopathy  

Heo, Deok-Hyun (Department of Neurology, Soonchunhyang University College of Medicine)
Jang, Il-Mi (Department of Neurology, Soonchunhyang University College of Medicine)
Roh, Hakjae (Department of Neurology, Soonchunhyang University College of Medicine)
Ahn, Moo-Young (Department of Neurology, Soonchunhyang University College of Medicine)
Jin, So-Young (Department of Pathology, Soonchunhyang University College of Medicine)
Publication Information
Annals of Clinical Neurophysiology / v.14, no.1, 2012 , pp. 36-40 More about this Journal
Abstract
Nephrogenic systemic fibrosis (NSF) is a systemic disease that affects the skin and other tissues in patients with renal insufficiency and exposure to gadolinium-containing contrast. A 55-year-old woman with end-stage renal disease on hemodialysis was consulted for progressive general weakness. After she had undergone multiple MRIs with gadolinium-containing contrast media, muscle weakness and skin lesions were developed. Her skin and muscle biopsy specimens showed CD34+ fibroblast entrapping collagen bundles. There are few reports of NSF with myopathy.
Keywords
Nephrogenic systemic fibrosis; Fibroblast; Myopathy;
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