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Increased Alcohol Decomposition Efficacy of Hoveina dulcis Extract by Carbohydrate-Hydrolyzing Enzymes  

Lee, Kyung-Seok (The Graduate School of Alternative Medicine of Kyonggi University)
Kim, Ae-Jung (The Graduate School of Alternative Medicine of Kyonggi University)
Lee, Ki-Young (Dept. of Food & Biotechnology, Hoseo University)
Publication Information
Journal of the East Asian Society of Dietary Life / v.22, no.4, 2012 , pp. 473-479 More about this Journal
Abstract
In this study, increased alcohol decomposition efficacy (ADH) of Hoveina dulcis extract by Carbohydrate-Hydrolyzing Enzymes was investigated. Carbohydrate decomposition enzymes such as Maxinvert (Invertase), Optidex L-400 (Glucoamylase) and Rohament CL (Cellulase & Pectinase) were added to Hoveina dulcis extract at different concentrations (0.01, 0.05, 0.1, 0.5 and 1%) for 48 hrs, after which samples were taken every 6 hrs for determination of ADH activity. As the enzyme concentration became higher, ADH activity also increased. Especially, the addition of 1% Rohament CL increased enzyme activity to 76% at 30 hrs incubation, after which the increase in activity stopped. In the rat and human body experiment, enzymatic decomposition of Hovenia dulcis extract by addition of 1% Rohament CL was also effective in decreasing serum alcohol concentration and respiration. Especially, in the early stage after alcohol consumption, the efficacy of enzyme treatment of Hovenia dulcis extract was more effective. These results show that if the glycoside forms of active compounds such as flavonols in Hovenia dulcis extract are converted into aglycone forms, alcohol decomposition capability can be enhanced.
Keywords
Hoveina dulcis; enzyme; alcohol; hangover;
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