Browse > Article

The Korean Perspective of Helicobacter pylori Infection: Lessons from Japan Policy to Prevent Gastric Cancer  

Lee, Sooyeon (CHA Cancer Prevention Research Center, CHA Cancer Institute, CHA University)
Park, Jong-Min (CHA Cancer Prevention Research Center, CHA Cancer Institute, CHA University)
Park, Sang-Ho (CHA Cancer Prevention Research Center, CHA Cancer Institute, CHA University)
Kim, Eun-Hee (CHA Cancer Prevention Research Center, CHA Cancer Institute, CHA University)
Hahm, Ki Baik (CHA Cancer Prevention Research Center, CHA Cancer Institute, CHA University)
Abstract
The guideline of the Korean College of Helicobacter and Upper Gastrointestinal Research group for Helicobacter pylori infection was first produced in 1998. Definite indication for H. pylori eradication is early gastric cancer in addition to the previous indications of peptic ulcer (PUD) including scar lesion and marginal zone B cell lymphoma (MALT type). Though treatment regimen was similar, Japan government declared the inclusion of H. pylori eradication in patients with H. pylori-associated chronic gastritis, suggesting the treatment guideline is quite different between Korea and Japan from February 21, 2013. The prime rationale of Japanese extended treatment guideline for H. pylori infection was based on the drastic intention to prevent gastric cancer according to their beliefs that H. pylori eradication can decrease gastric cancer incidence as well as mortality. In this review, the discrepancy in treatment guideline between Korea and Japan will be explained.
Keywords
Helicobacter pylori; Inflammation; Gastric cancer; Chemoprevention; siTRP;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 International Agency for Research on Cancer, World Health Organization. Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum 1994;61:1-241.
2 Asaka M. Helicobacter pylori infection and gastric cancer. Intern Med 2002;41:1-6.   DOI   ScienceOn
3 Asaka M, Kato M, Graham DY. Strategy for eliminating gastric cancer in Japan. Helicobacter 2010;15:486-90.   DOI   ScienceOn
4 Asaka M. A new approach for elimination of gastric cancer deaths in Japan. Int J Cancer 2013;132:1272-6.   DOI   ScienceOn
5 Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-917.   DOI   ScienceOn
6 Malfertheiner P, Sipponen P, Naumann M, Moayyedi P, Megraud F, Xiao SD, et al. Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critique. Am J Gastroenterol 2005;100:2100-15.   DOI   ScienceOn
7 Wu CY, Kuo KN, Wu MS, Chen YJ, Wang CB, Lin JT. Early Helicobacter pylori eradication decreases risk of gastric cancer in patients with peptic ulcer disease. Gastroenterology 2009;137:1641-8.e1-2.   DOI   ScienceOn
8 Fukase K, Kato M, Kikuchi S, Inoue K, Uemura N, Okamoto S, et al. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet 2008;372:392-7.   DOI   ScienceOn
9 Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001;345:784-9.   DOI   ScienceOn
10 Asaka M, Kato M, Takahashi S, Fukuda Y, Sugiyama T, Ota H, et al. Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition. Helicobacter 2010;15:1-20.
11 Lee SY. Future candidates for indications of Helicobacter pylori eradication: do the indications need to be revised? J Gastroenterol Hepatol 2012;27:200-11.   DOI   ScienceOn
12 Kim N, Kim JJ, Choe YH, Kim HS, Kim JI, Chung IS. Diagnosis and treatment guidelines for Helicobacter pylori infection in Korea. Korean J Gastroenterol 2009;54:269-78.   DOI   ScienceOn
13 Jee SR, Jung HK, Min BH, Choi KD, Rhee PL, Kang YW, et al. Guidelines for the treatment of functional dyspepsia. Korean J Gastroenterol 2011;57:67-81.   DOI   ScienceOn
14 Warren JR, Marshall BJ. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983;1:1273-5.
15 Hahm KB, Lee KM, Kim YB, Hong WS, Lee WH, Han SU, et al. Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice. Aliment Pharmacol Ther 2002;16 Suppl 2:115-27.
16 Han SU, Kim YB, Joo HJ, Hahm KB, Lee WH, Cho YK, et al. Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. J Gastroenterol Hepatol 2002;17:253-61.   DOI   ScienceOn
17 Kim YJ, Chung JW, Lee SJ, Choi KS, Kim JH, Hahm KB. Progression from chronic atrophic gastritis to gastric cancer; tangle, toggle, tackle with Korea red ginseng. J Clin-Biochem Nutr 2010;46:195-204.   DOI   ScienceOn
18 Chung JW, Hahm KB. Rejuvenation of atrophic gastritis in the elderly. J Gastroenterol Hepatol 2010;25:434-5.   DOI   ScienceOn
19 Lee JS, Paek NS, Kwon OS, Hahm KB. Anti-inflammatory actions of probiotics through activating suppressor of cytokine signaling (SOCS) expression and signaling in Helicobacter pylori infection: a novel mechanism. J Gastroenterol Hepatol 2010;25:194-202.   DOI   ScienceOn
20 Won I, Kim YJ, Kim SJ, Kim EH, Hahm KB. Nutrigenomic approach to tackle the unpleasant journey to Helicobacter pylori-associated gastric carcinogenesis. J Dig Dis 2011;12:157-64.   DOI   ScienceOn
21 Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013;63:11-30.   DOI   ScienceOn
22 Lee SY, Shin YW, Hahm KB. Phytoceuticals: mighty but ignored weapons against Helicobacter pylori infection. J Dig Dis 2008;9:129-39.   DOI   ScienceOn
23 Park S, Yeo M, Jin JH, Lee KM, Jung JY, Choue R, et al. Rescue of Helicobacter pylori -induced cytotoxicity by red ginseng. Dig Dis Sci 2005;50:1218-27.   DOI   ScienceOn
24 Chun KS, Kim EH, Lee S, Hahm KB. Chemoprevention of gastrointestinal cancer: the reality and the dream. Gut Liver 2013;7:137-49.   DOI   ScienceOn