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http://dx.doi.org/10.4174/jkss.2009.77.2.88

Annual Change of Clinicopathologic Characteristics after Radical Gastrectomy due to Gastric Cancer  

Park, Man-Woo (Department of Surgery, Yeungnam University College of Medicine)
Bae, Jung-Min (Department of Surgery, Yeungnam University College of Medicine)
Kim, Se-Won (Department of Surgery, Yeungnam University College of Medicine)
Kim, Sang-Woon (Department of Surgery, Yeungnam University College of Medicine)
Song, Sun-Kyo (Department of Surgery, Yeungnam University College of Medicine)
Publication Information
Annals of Surgical Treatment and Research / v.77, no.2, 2009 , pp. 88-95 More about this Journal
Abstract
Purpose: Recently, early gastric cancer has increased in Korea. Thus, endoscopic treatment and laparoscopic gastrectomy has increased in early gastric cancer patients. We studied periodic change and characteristics in gastric cancer patients. Thus, we analyzed annual change of clinicopathological characteristics and long-term survival results of gastric cancer patients after radical gastrectomy over 10 years. Methods: From 1995 to 2004, 2,387 patients underwent radical gastrectomy due to gastric cancer. We analyzed annual characteristics, sex, age distribution, cancer location, depth of invasion, lymph node metastasis, UICC stage and 5-year survival rates, retrospectively from medical records. Results: The number of gastric cancer patient has increased annually. The ratio of male to female was 2:1. Gastric cancer was most common and increased annually in the 60${\sim}$79-year age group. Early gastric cancer increased annually. The 5-year survival rate was 93% in stage Ia, 89% in stage Ib, 72% in stage II, 51% in stage IIIA, 38% in stage IIIb and 22% in stage IV. Multivariate analysis revealed that UICC stage (or depth of invasion and lymph node metastasis) and cancer location were the main independent prognostic factors. Conclusion: Prognosis is improved due to increase of early gastric cancer. So, we should attempt diagnosis early and treat early gastric cancer. Active treatment is recommended even for the elderly gastric cancer patients. And care should be taken with respect to morbidity and mortality.
Keywords
Gastric cancer; Gastrectomy; Clinicopathological characteristics;
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Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
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1 Ministry of Health and Welfare. Yearbook of Health and Welfare Statistics. Gwacheon, Korea: Ministry of Health and Welfare; 2007
2 Kim CH, Jang SW, Kang SH, Kim SW, Song SK. The significance of lymphatic, venous, and neural invasion as prognostic factors in patients with gastric cancer. J Korean Gastric Cancer Assoc 2005;5:113-9   DOI
3 Information Committee of the Korean Gastric Cancer Association. Current status of chemotherapy for gastric cancer patients in Korea - a nationwide survey. J Korean Surg Soc 2005;69:13-23
4 Smith BR, Stabile BE. Aggressive D2 lymphadenectomy is required for accurate pathologic staging of gastric adenocarcinoma. Am Surg 2006;72:849-52   PUBMED
5 Yoon KY, Lee SH, Choi KH. Comparison between proximal gastric cancer and distal gastric cancer. Korean J Gastroenterol 2002;40:241-6
6 Kim JP, Lee JH, Kim SJ, Yu HJ, Yang HK. Clinicopathologic characteristics and prognostic factors in 10,783 patients with gastric cancer. Gastric Cancer 1998;1:125-33   DOI   ScienceOn
7 Kim DY, Joo JK, Ryu SY, Park YK, Kim YJ, Kim SK. Clinicopathological characteristics and prognosis of carcinoma of the gastric cardia. Dig Surg 2006;23:313-8   DOI   ScienceOn
8 Shin HR, Jung KW, Won YJ, Kong HJ, Yim SH, Sung J, et al. National cancer incidence for the year 2002 in Korea. Cancer Res Treat 2007;39:139-49   DOI   ScienceOn
9 Kajiyama Y, Tsurumaru M, Udagawa H, Tsutsumi K, Kinoshita Y, Ueno M, et al. Prognostic factors in adenocarcinoma of the gastric cardia: pathologic stage analysis and multivariate regression analysis. J Clin Oncol 1997;15:2015-21   DOI
10 Blot WJ, Devesa SS, Kneller RW, Fraumeni JF Jr. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 1991;265:1287-9   DOI   ScienceOn
11 Lee YA, Jung GA, Min YD. Operative treatment of patients over 75 years old with gastric cancer. J Korean Gastric Cancer Assoc 2005;5:217-21   DOI
12 Noh SH, Yoo CH, Kim YI, Kim CB, Min JS, Lee KS. Results after a gastrectomy of 2,603 patients with gastric cancer: analysis of survival rate and prognostic factor. J Korean Surg Soc 1998;55:206-13
13 Fujiwara M, Kodera Y, Misawa K, Kinoshita M, Kinoshita T, Miura S, et al. Longterm outcomes of early-stage gastric carcinoma patients treated with laparoscopy-assisted surgery. J Am Coll Surg 2008;206:138-43   DOI   ScienceOn
14 Park JI, Jin SH, Bang HY, Paik NS, Moon NM, Lee JI. Survival rates after operation for gastric cancer: fifteen-year experience at a Korea Cancer Center Hospital. J Korean Gastric Cancer Assoc 2008;8:9-19   DOI
15 Diaz de Liano A, Yarnoz C, Aguilar R, Artieda C, Ortiz H. Rationale for gastrectomy with D2 lymphadenectomy in the treatment of gastric cancer. Gastric Cancer 2008;11:96-102   DOI   ScienceOn
16 Kim SH, Ahn SH, Park KC. General characteristics of gastric cancer of 3rd decade male patients. Korean J Gastroenterol 1991;4:857-65
17 Bonenkamp JJ, Hermans J, Sasako M, van de Velde CJ, Welvaart K, Songun I, et al. Extended lymph-node dissection for gastric cancer. N Engl J Med 1999;340:908-14   DOI   ScienceOn
18 Kang WS, Cheong O, Jeong MR, Kim HG, Ryu SY, Park YK, et al. Evaluation of the safety and feasibility of D2 lymphadenectomy in elderly patients with gastric cancer. J Korean Gastric Cancer Assoc 2008;8:85-90   DOI
19 Gretschel S, Estevez-Schwarz L, Hunerbein M, Schneider U, Schlag PM. Gastric cancer surgery in elderly patients. World J Surg 2006;30:1468-74   DOI   ScienceOn
20 Candela G, Sergio V, Di Libero L, Manetta F, Giordano M, Lanza M, et al. Prognostic and therapeutic value of D2 lymphadenectomy in the treatment of gastric cancer: experience of an Italian team. Chir Ital 2008;60:675-84   PUBMED
21 Song RJ, Kim SP, Min YD. Clinicopathologic characteristics and the prognosis of gastric cancer patients at both extremes of age. J Korean Gastric Cancer Assoc 2007;7:67-73   DOI
22 Bonenkamp JJ, Hermans J, Sasako M, van de Velde CJ, Welvaart K, Songun I, et al. Extended lymph-node dissection for gastric cancer. N Engl J Med 1999;340:908-14   DOI   ScienceOn
23 Ryu KW, Kim CS, Goo BH. Clinicopathologic characteristics of and prognosis for proximal gastric carcinomas. J Korean Surg Soc 2000;59:223-8
24 Ohno S, Tomisaki S, Oiwa H, Sakaguchi Y, Ichiyoshi Y, Maehara Y, et al. Clinicopathologic characteristics and outcome of adenocarcinoma of the human gastric cardia in comparison with carcinoma of other regions of the stomach. J Am Coll Surg 1995;180:577-82   PUBMED