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http://dx.doi.org/10.5187/jast.2021.e118

Fecal microbiome shifts by different forms of copper supplementations in growing pigs  

Kim, Minji (Animal Nutrition and Physiology Division, National Institute of Animal Science, Rural Development Administration)
Cho, Jae Hyoung (Department of Animal Resources Science, Dankook University)
Seong, Pil-Nam (Animal Nutrition and Physiology Division, National Institute of Animal Science, Rural Development Administration)
Jung, Hyunjung (Animal Nutrition and Physiology Division, National Institute of Animal Science, Rural Development Administration)
Jeong, Jin Young (Animal Nutrition and Physiology Division, National Institute of Animal Science, Rural Development Administration)
Kim, Sheena (Department of Animal Resources Science, Dankook University)
Kim, Hyeri (Department of Animal Resources Science, Dankook University)
Kim, Eun Sol (Department of Animal Resources Science, Dankook University)
Keum, Gi Beom (Department of Animal Resources Science, Dankook University)
Guevarra, Robin B. (Department of Animal Resources Science, Dankook University)
Kim, Hyeun Bum (Department of Animal Resources Science, Dankook University)
Publication Information
Journal of Animal Science and Technology / v.63, no.6, 2021 , pp. 1386-1396 More about this Journal
Abstract
Copper is an essential mineral for pigs, thus it is used as a feed additive in the forms of copper sulfate. Therefore, this study aimed at characterizing the fecal microbiota shifts in pigs as fed by different forms of copper supplementation. 40 growing pigs aged 73 ± 1 days with an average weight of 30.22 ± 1.92kg were randomly divided into 5 groups. The control group (CON) fed with basal diet, while treatment groups were fed a basal diet supplemented with 100 ppm/kg of copper sulfate (CuSO4), Cu-glycine complex (CuGly), Cu-amino acid complex (CuAA), and Cu-hydroxy(4methylthio)butanoate chelate complex (CuHMB) for 28 days of trial, respectively. The data presented the comparison between inorganic and organic copper supplementation through gut microbiota in growing pigs. Alpha and Beta diversity anaylsis resulted in copper supplementation did shifted gut microbioal community structure. At the phylum level, Firmicutes and Bacteroidetes were the most abundant phyla at all times regardless of treatment. At the genus level, the relative abundances of Prevotella, Lactobacillus, Megasphaera, and SMB53 of the CuGly and CuHMB groups were significantly higher than those of copper sulfate and basal diet groups. Overall, this study may provide the potential role of organic copper replacing inorganic copper, resulting in increased beneficial bacteria in the pig gut.
Keywords
Copper supplementation; Gut heatlth; Gut microbiome; Pigs;
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