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http://dx.doi.org/10.5187/jast.2021.e47

Complete genome sequence of serotype 3 Streptococcus suis INT-01, isolated from a domestic pig in Korea  

Park, Seon Young (Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology)
Kim, In Hwang (iNtRON Biotechnology)
Yu, Hyun Jin (iNtRON Biotechnology)
Paik, Hyoung Rok (iNtRON Biotechnology)
Son, Jee Soo (iNtRON Biotechnology)
Kim, Ji Hyung (Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology)
Publication Information
Journal of Animal Science and Technology / v.63, no.3, 2021 , pp. 662-665 More about this Journal
Abstract
Streptococcus suis is a major pig pathogen causing severe economic losses to the swine industry. This study aimed to analyze the genome of S. suis strain INT-01 isolated from a domestic pig in Korea. We found that the genome of strain INT-01 contains 2,092,054 bp, with a guanine (G) + cytosine (C) content of 41.3%, and the capsular polysaccharide synthesis locus of this strain is almost identical to that of serotype 3 S. suis strain 4961 isolated from China, suggesting that these isolates can be classified as serotype 3. Genomic analyses revealed that strain INT-01 is an extracellular protein factor (epf)-/ muraminidase-released protein (mrp)+/ suilysin (sly)- S. suis, which is the most prevalent genotype in Korea, and several virulence-related genes associated with the pathogenicity of S. suis were also detected. The genomic information of strain INT-01 may provide important insights into the development of control strategies against S. suis infections in Korea.
Keywords
Streptococcus suis; Pathogen; Genotype; Control strategy; Swine industry;
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