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http://dx.doi.org/10.5187/jast.2020.62.1.21

Dietary protease improves growth performance, nutrient digestibility, and intestinal morphology of weaned pigs  

Park, Sangwoo (Division of Animal and Dairy Science, Chungnam National University)
Lee, Jeong Jae (Division of Animal and Dairy Science, Chungnam National University)
Yang, Boung Mo (Division of Animal and Dairy Science, Chungnam National University)
Cho, Jin Ho (Division of Food and Animal Science, Chungbuk National University)
Kim, Soyun (Division of Animal and Dairy Science, Chungnam National University)
Kang, Joowon (Division of Animal and Dairy Science, Chungnam National University)
Oh, Sejong (Department of Animal Science, Chonnam National University)
Park, Dong-Jun (Korea Food Research Institute)
Perez-Maldonado, Rider (DSM Nutritional Products Asia Pacific)
Cho, Jee-Yeon (DSM Nutrition Korea Ltd.)
Park, Il-Hun (DSM Nutrition Korea Ltd.)
Kim, Hyeun Bum (Department of Animal Resources Science, Dankook University)
Song, Minho (Division of Animal and Dairy Science, Chungnam National University)
Publication Information
Journal of Animal Science and Technology / v.62, no.1, 2020 , pp. 21-30 More about this Journal
Abstract
This study was conducted to evaluate effects of dietary protease (PR) on growth performance, nutrient digestibility, and intestinal morphology of weaned pigs. A total of 75 weaned pigs [7.06 ± 0.18 kg of average body weight (BW); 28 day old] were randomly allotted to 3 dietary treatments in a randomized complete block design (blocks = BW and sex): a diet based on corn and soybean meal to meet the requirement of crude protein (CP) as a positive control (PC; CP = 24.49%), a low protein diet as a negative control (NC; CP = 22.51%), and NC + 0.02% PR. The PR used in this study was a commercial product containing 75,000 protease units/g derived from Nocardiopsis prasina produced in Bacillus licheniformis. Pigs were fed the dietary treatments for 6 weeks and the diets containing 0.2% chromic oxide for the last week of this study. Blood, feces, ileal digesta, and ileum samples were collected from randomly selected two pigs in each pen on respective time points. Measurements were growth performance, apparent ileal digestibility (AID) and apparent total tract digestibility (ATTD) of dry matter (DM), CP, and energy, frequency of diarrhea, packed cell volume (PCV), and ileal morphology of weaned pigs. Pigs fed PC and PR had higher (p < 0.05) final BW, average daily gain (ADG), and gain to feed ratio (G:F) during overall experimental period than those fed NC. Pigs fed PC and PR had higher (p < 0.05) AID or ATTD of DM, CP, or energy than those fed NC. Moreover, pigs fed PR had higher ratio between villus height and crypt depth (p < 0.05) and number of goblet cells (p < 0.05) than those fed NC. Addition of PR decreased (p < 0.05) frequency of diarrhea for the first two weeks after weaning compared with PC and NC. In addition, pigs fed PR had lower (p < 0.05) PCV on d 14 after weaning than those fed PC and NC. In conclusion, addition of PR in nursery diets with a low protein level significantly improved growth performance, nutrient digestibility, and intestinal morphology of weaned pigs.
Keywords
Growth performance; Intestinal morphology; Nutrient digestibility; Protease; Weaned pigs;
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Times Cited By KSCI : 12  (Citation Analysis)
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