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http://dx.doi.org/10.5187/JAST.2009.51.3.231

Effects of Polyclonal Antibodies to Abdominal and Subcutaneous Adipocytes on Ruminal Fermentation Patterns and Blood Metabolites in Korean Native Steers  

Choi, Chang-Weon (National Institute of Animal Science, RDA)
Baek, Kyung-Hoon (Yeungnam University)
Kim, Sung-Jin (National Institute of Animal Science, RDA)
Oh, Young-Kyoon (National Institute of Animal Science, RDA)
Hong, Seong-Koo (National Institute of Animal Science, RDA)
Kwon, Eung-Gi (National Institute of Animal Science, RDA)
Song, Man-Kang (Chungbuk National University)
Choi, Chang-Bon (Yeungnam University)
Publication Information
Journal of Animal Science and Technology / v.51, no.3, 2009 , pp. 231-240 More about this Journal
Abstract
Sixteen ruminally cannulated Korean native steers (Hanwoo; $626.2\pm47.72$ kg) were used to investigate the effects of polyclonal antibodies against abdominal (AAb) and subcutaneous adipocyte membrane proteins (SAb) on ruminal fermentation patterns and blood metabolites. The body weight (BW) of Hanwoo was decreased 2-weeks after AAb and SAb injection, BW reduction was also observed in control and non-immunized serum groups, indicating that stress induced by other factors (e.g. blood sampling etc.) rather than antibodies injection may affect the BW reduction. Antibodies treatment did not affect (P > 0.05) rumen pH, volatile fatty acids and ammonia-N concentration. The ranges were similar with typical ranges of those in Hanwoo. Compared with control, blood urea N concentration was decreased in AAb group and increased (P < 0.05) in SAb group before antibodies treatment. However, none of the groups were significantly (P > 0.05) affected at 2- or 4-weeks after the treatment. Concentration of plasma glucose in the non-immunized serum group was significantly higher (P < 0.05) than the other groups at 0-week after treatment. However, antibodies treatment did not affect the concentration of plasma glucose. Concentration of plasma triglyceride showed no difference (P > 0.05) between the groups and ranged from 11.4 to 19.9 mg/dl, which is the perfect range of plasma triglyceride of Hanwoo fed concentrate based diets. In conclusion, these results may indicate that the present AAb and SAb have safety in nutritional physiological metabolism in Hanwoo. Further study on in vivo fat reduction of the antibodies against abdominal and subcutaneous adipocytes PMPs of Hanwoo is required for inedible fat-reduced high quality beef production.
Keywords
Hanwoo; Polyclonal antibody; Ruminal fermentation; Blood metabolites; Fat;
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