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http://dx.doi.org/10.5187/JAST.2009.51.3.193

Commercial Application of Porcine MC1R Gene Polymorphisms to Korean Pork Industry  

Ha, You-Kyoung (Department of Animal Science, Chungbuk National University)
Choi, Jung-Suk (Department of Animal Science, Chungbuk National University)
Kim, Sang-Wook (Department of Animal Science, Chungbuk National University)
Choi, Yang-Il (Department of Animal Science, Chungbuk National University)
Lee, Seug-Soo (National Livestock Research Institute)
Choi, Jae-Won (ChungBuk Institute of Livestock and Veterinary Research)
Jeon, Soon-Hong (ChungBuk Institute of Livestock and Veterinary Research)
Kim, Kwan-Suk (Department of Animal Science, Chungbuk National University)
Publication Information
Journal of Animal Science and Technology / v.51, no.3, 2009 , pp. 193-200 More about this Journal
Abstract
The pork from black-coated pigs is famous among-consumers for better eating quality. The loci affecting black coat color was identified in pig chromosome 6 in which several genetic effects on pork quality have been reported. The melanocortin 1 receptor (MC1R) gene is a major gene which plays a key role in regulation of eumelanin (black/brown) and phaeomelanin (red/yellow). In this study, the MC1R gene polymorphism was analyzed for pig breed determination and genetic association with pork quality traits. MC1R Ala243Thr variation was analyzed to determine a specific genotype for four commercial pig breeds (Landrace, Yorkshire, Berkshire and, Duroc) and a Korean native pigs (KNP). Then we developed original KNP-specific DNA markers to determine the pork from black-coated pigs using MC1R DNA sequences. The total length of the MC1R coding sequence ranged 1451bp in KNP. KNP had the 0201 allele pertaining to $E^{D1}$ but some of the KNP had the $E^P$ allele, probably reflecting the geneticintrogression of $E^P$ allele into KNP. Furthermore, a relationship between Leu102Pro single nucleotide polymorphism (SNP) genotype and pork quality phenotype were analyzed in F2 reciprocal-crossbred population between KNP and Yorkshire. Association analysis indicated that the allele of the MC1R gene has no effect on pork quality. These results suggest that black coat-color is not directly associated with preferred pork quality, but the black-coat color pig breed may have other genetic components for superior pork quality.
Keywords
MC1R; KNP; Polymorphism; Pork quality;
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