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http://dx.doi.org/10.5187/JAST.2007.49.5.569

Effects of a Porcine MC4R Polymorphism(892G>A) on Carcass Traits in Commercial Pigs  

Han, S.H. (National Institute of Subtropical Agriculture, RDA)
Lee, S.S. (National Institute of Subtropical Agriculture, RDA)
Ko, M.S. (National Institute of Subtropical Agriculture, RDA)
Seong, P.N. (National Institute of Animal Science, RDA)
Park, B.Y. (National Institute of Animal Science, RDA)
Cho, I.C. (National Institute of Subtropical Agriculture, RDA)
Publication Information
Journal of Animal Science and Technology / v.49, no.5, 2007 , pp. 569-576 More about this Journal
Abstract
receptor(MC4R) gene and carcass traits was examined in randomly selected commercial pigs. A porcine MC4R gene was genotyped for Asp298Asn(nt. 892G>A) by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). A total of three genotypes, A/A, A/G, and G/G, were found with 28.8, 22.8, and 48.4% frequencies, respectively. In the whole population, pigs containing 892A/- showed significantly higher marbling score than those of homozygotes G/G(P<0.05). Two homozygotes, A/A and G/G showed lower in meat color score but higher in water holding capacity than those of heterozygotes A/G(P<0.01). However, the carcass weight of the barrows containing wild type -/G was significantly higher(i.e. more than 2.5kg) than those of homozygotes A/A(P<0.05). The effects of each genotype on carcass traits in the gilts were similar to those of the whole population, but not in barrows, suggesting an unknown sex-related effect on carcass traits. This study suggested that the genotype MC4R A/- could improve the meat quality in the commercial pig production. However, since the genetic polymorphism of MC4R gene differentially affected the carcass traits in sex-related manner, therefore, both parameters, the sex and genotype, should be considered for marker-assisted selection in commercial pig production.
Keywords
Association; MC4R; Genotype; Mutation; Sex-related manner; Pig;
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