Browse > Article
http://dx.doi.org/10.5187/JAST.2006.48.5.663

Effects of Slow Release Recombinant Porcine Somatotropin (rpST) Administration on Growth Performance and pST and IGF-1 of Blood in Finishing Pigs  

김영화 (National Livestock Research Institute, RDA)
문홍길 (National Livestock Research Institute, RDA)
박준철 (National Livestock Research Institute, RDA)
정현정 (National Livestock Research Institute, RDA)
김인철 (National Livestock Research Institute, RDA)
이상진 (National Livestock Research Institute, RDA)
장병선 (Animal Health Research Institute, Life Sciences R&D, LG Chemistry Investment, Ltd)
정정수 (Department of Animals Science, Chungbuk National University)
정일병 (National Livestock Research Institute, RDA)
Publication Information
Journal of Animal Science and Technology / v.48, no.5, 2006 , pp. 663-670 More about this Journal
Abstract
The present study was performed to investigate the effect of plant type recombinant porcine somatotropin (pST) adminstration on growth performance and blood profile of finishing pigs. Forty-eight Landrace barrows weighing 78 kg were employed for six week growth trial. Twelve barrows were allocated into various rpST types ; the control (CONT), the 4:1 type rpST (TRT 1), the 1:1 type rpST (TRT 2); and the 4:1 type rpST group(TRT 3) respectively. CONT group were not planted rpST. TRT 1 group was treated with rpST once a week for 6 weeks. Each dose contained the rpST equivalent to 100mg from initial to two weeks and 125mg from three weeks to finial week. TRT 2 and TRT 3 groups were planted rpST four times contained the rpST equivalent to 100mg during trial period from initial to two weeks, and 125 mg from three weeks, to four weeks, respectively. All pigs were fed a commercial feed containing 0.9% lysine ad lib. Daily gain increased by 19.4% in TRT 1(p<0.05) compared to the CONT. rpST improved feed/gain by 13.4~28.9% in all treatment groups(p<0.05). Back fat thickness of the all rpST treated groups were 23.3~29.2% thinner than that of the CONT. These results indicated that the rpST stimulated growth performance in finishing pigs and plant type rpST could be used as a growth stimulant for finishing pigs.
Keywords
rpST; Finishing pigs; Growth performance; Back fat thickness;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Etherton, T. D., Wiggins, J. P., Evock, C. M., Chung, C. S., Rebhun, J. F., Walton, P. E. and Steele, N. C. 1987. Stimulation of pig growth performance by porcine growth hormone Determination of the does-response relationship. J. Anim. Sci. 63:433-443
2 Evans, H. M. and Long, J. A. 1922. Characteristic effects upon growth, oestrus and ovulation induced by the intraperitoneal administration of fresh anterior hypophyseal substance. Proc. Natl. Acad. Sci. USA. 8:38-39
3 Knight, C. D., Kasser, T. R., Swenson, G. H., Hintz, R. L., Azain, M. J., Bates, R. O., Cline, T. R., Crenshaw, J. D., Cromwell, G. L., Hedrick, H. B., Jones, S. T., Kropf, D. H., Lewis, A. J., Mahan, D. C, Mckeith, F. M., McLaughlin, C. L., Nelssen, J. L., Novakofski, J. E., Orcutt, M. W. and Parrett, N. A. 1991. The performance and carcass composition response of finishing swine to a range of porcine somatotropin doses in a l-week delivery system. J. Anim, Sci. 69:4678-4689   DOI
4 Meisinger, D. J. 1989. Question and dnswers about porcine somatotropin. Pitman-Moore, Persornal Communication
5 SAS. 1995. SAA/STAT User's Guide : Version 6, 11th edition. SAS Institute Inc., Cary, NC
6 Smith, V. G. and Kasson, C. W. 1991. The interrelationship between crude protein and exogenous porcine somatotropin on growth, feed and carcass measurements of pigs. J. Anim. Sci. 69: 571-577   DOI
7 Wolverton, C. K., Azain, M. J., Duffy, J. Y., White, M. E. and Ramsay, T. G. 1992. Influence of somatotropin on lipid metabolism and IGF gene expression in porcine adipose tissue. Am. J. Physiol. Endocrinol. Metab. 263:E637-E645
8 Brameld, J. M., Atkinson, J. L., Saunders, J. C, Pell, J. M., Buttery, P. J. and Gilmour, R. S. 1996. Effects of growth hormone administration and ditary protein intake on insulin-like growth factor I and growth hormone receptor mRNA expression in porcine liver, skeletal muscle, and adipose tissue. J. Anim. Sci. 74:1832-1841
9 Campbell, R. G., Steele, N. C., Capema, T. J., McMurtry, J. P., Solomon, M., Solomon, B. and Mitchell, A D. 1989. Interrelationships between sex and exogenous growth hormone administration on performance body composition and protein and fat accretion of growing pigs. J. Anim. Sci. 67:177-186   DOI
10 Chilliard, Y. 1990. Long-term effects of recombinant bovine somatotropin (rbST). In use of Somatotropin in Livestock Production(Sejrsen K., Vestergaard, M. and Niemann-Sorensen, A, aditors). Elsevier Applied Science New York
11 Chung, C. S., Meserole, V. K. and Etherton, T. D. 1983. Temporal nature of insulin binding and insulin-stimulated glucose metabolism in isolated swine adippoytes. J. Anim. Sci. 56:58-63   DOI
12 Evock, C. M., Etherton, T. D., Chung, C. S. and Ivy, R. E. 1988. Pituitary porcine growth hormone (pGH) and a recombinant pGH analog stimulate pig growth performance in a similar manner. J. Anim. Sci. 66:1928-1941   DOI
13 Joo, S. T., Kauffman, R. G., Kim, B. C. and Park, G. B. 1999. The relationship of sarcoplasmic myofibrillar protein solubility to colour and water-holding capacity in porcine longissius muscle. Meat Sci. 52:291-297   DOI   ScienceOn
14 Garssen, G. S. and Oldenbroek, J. K. 1992. Somatotropins in animal production. In : N. A. A. Macfarlane(Ed.) Biotechnological Innovations in Animal productivity. Butterworth-Heinemann Ltd., Oxford
15 Goodband, R. D., Nelssen, J. L., Hines, R. H., Kropf, D. H., Thaler, R. C, Schricker, B. R., Fitzner, G. E. and Lewis, A. J. 1990. The effects of porcine somatotropin and dietary lysine on growth performance and carcass characteristics of finishing swine. J. Anim. Sci. 68:3261-3276   DOI
16 Joo, S. T., Kauffman R. G., Kim, B. C. and Kim, C. J. 1995. The relationship between color and water-holding capacity in postrigor porcine longissimus muscle. J. Muscle Foods. 6:211-226   DOI   ScienceOn
17 Alan, L. R. 1990. Safety and efficacy of sustained-release recombinantly derived bovine somatotropin administered to lactating dairy cows. Graduate Thesis Minnesota Univ
18 Hacker, R. R., Deschutter, A., Adeola, O. and Kasser, T. R. 1993. Evaluation of long-term somatotropin implants in finishing pigs. J. Anim. Sci. 71:564-570
19 Hadlay, M. E. 1988. Endocrinology(2nd ed.). Prentile-Hall Intrl. INC., New Jersey
20 Boyd, R. D., Bauman, D. E., Beerman, D. H., DeNeergard, A. F., Souza, L. and Butler, W. R. 1986. Titration of the porcine growth hormone dose which maximizes growth performance and lean deposition in swine. J. Anim. Sci. 63 (Suppl. 1):218
21 Etherton, T. D. and Chung, C. S. 1981. Preparation, characterization, and insulin sensitivity of isolated swine adipocytes : Comparison with adipose tissueslices. J. Lipid Res. 22:1053-1059
22 Boyd, R. D. and Bauman, D. E. 1988. Mechanisms of action for somatotropin in growth. In : Campion, D. R., Hausman, G. J. and artin, R, J. (Eds.) Animal growth regulation. Plenum Press. pp. 257-284
23 Clemmons, D. L., Klibanski, A., Underwood, L. E., McArthur, J. W., Ridgway, E. C, Beithins, I. Z. and Van Wyk, J. J. 1981. Reduction of plasma immunoreactive somatomedic-C. J. Clin. Endocrinol. Metab. 53:1247-1250   DOI
24 Dunshea, F. R., Bauman, D. E., Boyd, R. D. and Bell, A. W. 1992. Temporal response of circulating metabolites and hormones during somatotropin treatment of growing pigs. J. Anim. Sci. 70: 123-131   DOI