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http://dx.doi.org/10.5187/JAST.2005.47.3.439

Effect of Recombinant Bovine Somatotropin Injections on Deer Stag Plasma Insulin-like Growth Factor-I Profiles  

Shin, H.T. (Department of Food Biotechnology, Sungkyunkwan University)
Cui, S.H. (Department of Food Biotechnology, Sungkyunkwan University)
Chung, K.W. (Department of Food Biotechnology, Sungkyunkwan University)
Ahn, J.N. (Department of Food Biotechnology, Sungkyunkwan University)
Baig, S.Y. (Department of Food Biotechnology, Sungkyunkwan University)
Publication Information
Journal of Animal Science and Technology / v.47, no.3, 2005 , pp. 439-446 More about this Journal
Abstract
This study was conducted to elucidate the influence of recombinant bovine somatotropin (rBST) on the plasma IGF-I profiles in deer stags. Slow release rBST (250mg each) preparations were injected subcutaneously during the antler's non-growing period and growing period. It was observed that significant increases in the plasma IGF-I concentrations were occurred right after injections of the rBST irrespective of antler's non-growing period or growing period. When the rBST preparations were injected two times with one week interval during the antler's non-growing period, the mean level of IGF-I was found to be 2,920.7ng I mL, indicating that the IGF-I concentration increased up to 8.4-folds compared with a control. After two weeks from second shot, however, the IGF-I levels decreased to the level of the control. Similar results were also obtained with both a Sika and a Red deer during the antler's growing period. Increases in the IGF-I level of up to 5.6-folds with the Sika deer and 4.3-folds with the Red deer were found. Based on the present study, it is likely that the rBST may be used as a possible candidate for an antler's growth stimulating agent.
Keywords
Sika deer; Red deer; Antler; rBST; IGF-I;
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