Browse > Article
http://dx.doi.org/10.5187/JAST.2004.46.6.903

Characteristics and Frequencies of Alternative Initiation Codon(AIC) of mtDNA ND2 in Five Pig Breeds  

Han, S.H. (National Institute of Subtropical Agriculture, R.D.A)
Cho, I.C (National Institute of Subtropical Agriculture, R.D.A)
Choi, Y.L. (National Institute of Subtropical Agriculture, R.D.A)
Lee, C.E. (National Institute of Subtropical Agriculture, R.D.A)
Ko, M,S. (National Institute of Subtropical Agriculture, R.D.A)
Kim, J.H. (Division of Applied Life Science, Gyeongsang National University)
Seo, B.Y. (Division of Applied Life Science, Gyeongsang National University)
Lee, J.G. (Division of Applied Life Science, Gyeongsang National University)
Jeon, J.T. (Division of Applied Life Science, Gyeongsang National University)
Publication Information
Journal of Animal Science and Technology / v.46, no.6, 2004 , pp. 903-908 More about this Journal
Abstract
Alternative initiation codon(AlC) has been reported in the mitochondrial genes in various mammalian species. We investigated the AlC of mitochondrial NADH dehydrogenase 2 gene(rntDNA ND2) in five pig breeds. Two kinds of initiation codons(ATA/ATf) showing different frequencies among tested pig breeds were used. While all Large White pigs had ATA as an initiator methionine codon, all Landrace pigs had ATf. The other breeds(Berkshire, Duroc and Hampshire) had both initiation codons with the ATA frequencies, 91.9, 21.3 and 60.00/0, respectively. In the previous reports, all Chinese indigenous pig breeds were identified to have unique initiation codon ATA. Although the effect of Ale on the translation of mtDNA ND2 has not been studied in this study, AlC patterns in mtDNA ND2 will contribute to the maternity test using molecular markers in pig breeding.
Keywords
Alternative initiation codon; mtDNA; ND2; Breed-specific; Maternity test;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Brown, W. M., George, M. and Wilson, A. C. 1979. Rapid evolution of animal mitocondrial DNA Proc. Natl. Acad. Sci. USA 76:1967-1971.   DOI   ScienceOn
2 Cann, R. L., Brown, W. M. and Wilson, A. C. 1984. Polymorphic sites and the mechanism of evolution in human mitochondrial DNA Genetics. 325:31-36.
3 Coble, M. D., Just, R S., O'Cailaghan, J. E., Letmanyi, I. H., Peterson, C. T., Irwin, J. A and Parsons, T. J. 2004. Single nucleotide polymorphisms over the entire mtDNA genome that increase the power of forensic testing in Caucasians. Int. J. Legal. Med. In press.
4 Giles, R E., Blanc, H., Cann, H. M. and Wallace, D. C. 1980. Maternal inheritance of human mitochondrial DNA Proc. Natl. Acad. Sci. USA 77:6715-6719.   DOI   ScienceOn
5 Giuffra, E., Kijas, J. M. H., Amarger, V., Carlborg, O., Jeon, J. T. and Andersson, L. 2000. The origin of the domestic pig: independent domestication and subsequent introgression. Genetics. 154:1785-1791.
6 Huang, Y., Shi, X. and Zhang, Y. 1999. Mitochondrial genetic variation in Chinese pigs and wild boars. Biochem. Genet. 37:335-343.
7 Janke, A, Magnell, O., Wieczorek, G., Westerman, M. and Amason, U. 2002. Phylogenetic analysis of 18S rRNA and the mitochondrial genomes of the wombat, Vombatus ursinus, and the spiny anteater, Tachyglossus aculeatus: increased support for the Marsupionta hypothesis J. Mol. Evol. 54:71-80.
8 Lin, C. S., Sun, Y. L., Liu, C. Y., Yang, P. C, Chang, L. C, Cheng, I. C, Mao, S. J. and Huang, M. C. 1999. Complete nucleotide sequence of pig(Sus serofa) mitochondrial genome and dating evolutionary divergence within Artiodactyla. Gene. 236:107-114.   DOI   ScienceOn
9 Lopez, J. Y., Cevario, S. and O'Brien, S. J. 1996. Complete nucleotide sequences of the domestic cat(Felis eatus) mitochondrial genome and a transposed mtDNA tandem repeat(Numt) in the nuclear genome. Genomics. 33:229-246.   DOI   ScienceOn
10 Okumura, N., Ishiguro, N., Nakano, M., Katsuya, H., Matsui, A. and Sahara, M. 1996. Geographic population structure and sequence divergence in the mitochondrial DNA control region of the Japanese wild boar(Sus scrofa leucomystax), with reference to those of domestic pigs. Biochem. Genet. 34:179-189.
11 Ursing, B. M. and Amason, U. 1998. The complete mitochondrial DNA sequence of the pig(Sus scrofa). J. Mol. Evol. 47:302-306.
12 Watanabe, T., Hayashi, Y., Ogasawara, N. and Tomita, T. 1985. Polymorphism of mitochondrial DNA in pigs based on restnction endonuclease cleavage patterns. Biochem. Genet. 23:105-113.
13 Watanabe, T., Ishiguro, N., Nakano, M., Matsui, A., Hongo, H., Yamazaki, K. and Takahashi, O. 2004. Prehistoric Sado Island populations of Sus scroja distinguished from contemporary Japanese wild boar by ancient mitochondrial DNA. Zoolog. Sci. 21:219-228.
14 Alves, E., Ovilo, C., Rodriguez, M. C. and Silio, L. 2003. Mitochondrial DNA sequence variation and phylogenetic relationships among Iberian pigs and other domestic and wild pig populations. Anim. Genet. 34:319-324.
15 Anderson S., Bankier, A. T., Barrell, B. G., Bruijin, M. H. L., Coulson, A. R., Drouin, J., Eperon, I. C, Nierlich, C. D., Roe, B. A, Sanger, F., Schreier, P. H., Smith, A. J., Staden, R and Young, I. G. 1981. Sequence and organization of the human mitochondrial genome. Nature. 290:457-465.   DOI   ScienceOn
16 Amason, U. and Gullberg, A 1993. Comparison between the complete mtDNA sequences of the blue and the fin whale, two species that can hy-bridize in nature. J. Mol. Evol. 37:312-322.
17 Kijas, J. M. H. and Andersson, L. 2001. A phylogenetic study of the domestic pig estimated from the near-complete mtDNA genome. J. Mol. Evol. 52:302-308.
18 Bokonyi, S. 1974. History of Domestic Mammals in Central and Eastern Europe. Academiai Kiado, Budapest.
19 Jones, G. F. 1998. Genetic aspects of domestication, common breeds and their origins. In: Ruvinsky, A, Rothschild, M. E The genetics of the pig. 17-50.
20 Kijas J. M. H., Wales, R, Tomsten, A, Chardon, P., Moller, M and Andersson, L. 1998. Melanocortin receptor I(MC1R) mutations and coat color in pigs. Genetics. 150:1177-1185.
21 조인철, 정용환, 정진관, 성필남, 김병우, 이정규, 전진태. 2003. Sungle stranded conformation poly-morphism 분석에 의한 돼지 Duroc 품종의 미토 콘드리아 DNA 유전적 변이. 한국동물자원과학회지. 45:911-916
22 Kim, K. I., Lee, J. H., Li, K., Zhang, Y. P., Lee, S. S., Gongora, J. and Moran, C. 2002. Phylogenetic relationships of Asian and European pig breeds determined by mitochondrial DNA D-loop sequence polymorphism. Anim. Genet. 33:19-25.
23 Wilson, A. C, Cann, L., Carr, S. M., George, M. and Gyllensten, U. B. 1985. Mitochondrial DNA and two perspectives on evolutionary genetics. Biol. J. Linn. Soc. 26:375-400.   DOI
24 Yang, J., Wang, J., Kijas, J., Liu, B., Han, H., Yu, M., Yang, H., Zhao, S. and Li, K. 2003. Genetic diversity present within the near-complete mtDNA genome of 17 breeds of indigenous Chinese pigs. J. Hered. 94:381-385   DOI   ScienceOn