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Antidiabetic Activities Analysis by Oral Glucose Tolerance Test in Rats  

Kang, Myung-Hwa (Dept. of Food Science and Nutrition, Hoseo University)
Choi, Mi-Kyeong (Dept. of Food and Nutrition, Kongju National University)
Publication Information
Reproductive and Developmental Biology / v.34, no.4, 2010 , pp. 305-308 More about this Journal
Abstract
In this study, we conducted an oral glucose tolerance test (OGTT) so as to compare antidiabetic activities of general potatoes, purple-flesh potatoes, and potato pigments in rats at various concentration levels. After allowing the rats to abstain from food for 12 hours, 10%/20% general potato, purple-flesh potato, and potato extract was orally administered to rats at 100 and 500 mg/kg concentrations. The blood glucose level was measured after an hour. Then, immediately, 1.5 g/kg of sucrose was administered through the abdominal cavity and the blood glucose measured after 30, 60, 120, and 180 minutes. 20% purple-flesh potato group and 10% general potato group, both 100 and 500 mg/kg, showed a significant concentration-dependent decrease in blood glucose levels after 30 minutes. The 100 mg/kg potato pigment group also showed a statistically significant decrease after 30 minutes. In conclusion, administration of 10% general potato, 20% purple-flesh potato, and potato pigment can reduce blood glucose level in an OGTT using rats.
Keywords
OGTT; Potato; Antidiabetic Activities; Rats;
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Times Cited By KSCI : 1  (Citation Analysis)
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