Browse > Article

Effects of Progestagens on Estrous Synchronization and Superovulation in Korean Native Goats  

송태헌 (충남대학교 동물자원학부)
한만희 (축산기술연구소)
천행수 (충남대학교 동물자원학부)
박병권 (공주대학교 영상보건대학 특수동물학과)
서길웅 (충남대학교 동물자원학부)
이규승 (충남대학교 동물자원학부)
Publication Information
Abstract
This study was conducted to determine the effects of progestagen (Synchromate-B, Veramix, CIDR) and hormone (PMSG, FSH, hCG) treatments on superovulation and estrous synchronization in Korean native goats. Goats were initially superovulated by using progestagens (Synchromate-B, Veramix, CIDR) and hormones (FSH, PMSG, hCG). The progestagens were removed after 15 days of insertion and 0.88 mg of FSH was injected intramuscularly twice a day from day 12 to day 15. In addition, 150 IU of PMSG and 200 IU hCG were injected intramuscularly in the morning of day 12 and in the afternoon of day 15, respectively. Estrous synchronization was induced by the progestagen releasing devices for 13 days and intramuscular injection of 400 IU PMSG in the morning of day 11. The results were summarized as follows: 1. The responses of superovulation treated with three types (Synchromate-B, Veramix, CIDR) of progestagen were 98.6, 99.4 and 98.8%, respectively. The average ovulation rates with Synchromate-B, Veramix and CIDR were 12.58 $\pm$ 6.52, 12.91 $\pm$ 7.27 and 11.28 $\pm$ 6.33, respectively. The average ovulation rates of Synchromate-B and Veramix treatments were significantly higher than that of the CIDR treatment (P<0.05). 2. The responses of estrus synchronization treated with Synchromate-B, Veramix and CIDR were 52.9, 72.9 and 75.7%, respectively. Veramix and CIDR treatments on estrous synchronization were significantly higher than the Synchromate-B treatment (P<0.05). Among the estrous synchronized goats, the estrous ovulation rates with Synchromate-B, Veramix and CIDR were 2.11 $\pm$ 1.89, 1.35 $\pm$ 0.87 and 1.43 $\pm$ 0.96, respectively. The estrous ovulation rates of the Synchromate-B treatment were significantly higher than those of the other treatments (P<0.05). 3. The average superovulation rates were 11.76 $\pm$ 6.00 and 11.07 $\pm$ 6.46 for the PMSG treatment and control groups, showing that there was no PMSG effects for the superovulation treated with CIDR.
Keywords
Korean native goat; Progestagen; Superovulation; Estrous synchronization;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Ahmed, M. M., Makawi, S. E. and Jubara, A. S. 1998. Synchroization of oestrus in Nubian goats. Small Ruminant Res. 30:113-120   DOI   ScienceOn
2 Ebert, K. M., Selgrath, J. P., DiTullio, P., Denman, J., Smith, T. E., Memon, M. A., Schindler, J. E., Monastersky, G. M., Vital, J. A. and Gordon, K. 1991. Transgenic production of a variant of human tissue-type plasminogen activator in goat milk: Generation of transgenic goats and analysis of expression. Bio/Technology 9:835-838
3 Ko, J. H., Lee, C. S., Kim, K. H., Pang, M. G., Koo, J. S., Fang, N., Koo, D. B., Oh, K. B., Yoon, W. S., Zheng, G. D., Park, J. S., Kim, S. J., Han, Y. M., Choi, I. Y., Lim, J., Shin, S. T., Jin, S. W., Lee, K. K. and Yoo, O. J. 2000. Production of biologically active human granulocyte colony stimulating factor in the milk of transgenic goat. Transgenic Res. 9:215-222   DOI   ScienceOn
4 Motlomelo, K. C., Greyling, J. P. C. and Schwalbach, L. M. J. 2002. Synchronisation of estrus in goats: the use of different progestagen treatments. Small Ruminant Res. 45:45-49
5 Wheaton, J. E., Carlson, K. M., Windels, H. F. and Johnston, L. J. 1993. CIDR-a new progesterone-releasing intravaginal device for induction of estrus and cycle control in sheep and goats. Anim. Reprod. Sci. 33:127-141   DOI   ScienceOn
6 Senn, B. J and Richardson, M. E. 1992. Seasonal effects on caprine response to synchronization of estrus and superovulatiory treatment. Theriogenology 87:359-365
7 Wright, G., Carver, A., Cottom, D., Reeves, D., Scott, A., Simons, P., Wilmut, I., Garner, I. and Colman, A. 1991. High level expression of active human alpha-I-antitrypsin in the milk of transgenic sheep. Biotechnology 9:830-840
8 Thompson, J. G. E., Simpson, A. C., James, R. W. and Tervit, H. R. 1990. The application of progesterone-containing CIDR devices to superovulated ewes. Thriogenology 33:1297-1304   DOI   ScienceOn
9 Van Cleeff, J., Karsch, F. J. and Padmanabhan, V. 1998. Characterization of endocrine events during the periestrous period in sheep after estrous synchronization with controlled internal drug release (CIDR) device. Domest. Anim. Endocrinol. 15:23-34
10 Cameron, A. W. N., Battye, K. M. and Trounson, A. O. 1988. Time of ovulation in goats (Capra hircus) induced to superovulate with PMSG. Reprod. Fertil, Dev. 83:747-752   DOI
11 Pampoukidou, A., Alifakiotis, T., Avdi, M. and Magra, I. 1992. Superovulation and embryo transfer in goats by using PMSG or FSH. Proceedings of the 8th Meeting European Embryo Transfer Association (Lyon), p. 198
12 Lee, C. S., Fang, N. Z., Koo, D. B., Lee, Y. S., Zheng, G. D., Oh, K. B., Youn, W. S., Han, Y. M., Kim, S. J., Lim, J. H., Shin, S. T., Jin, S. W., Lee, K. S., Ko, J. H., Koo, J. S., Park, C. S., Yoo, O. J. and Lee, K. K. 2000. Embryo recovery and transfer for the production of transgenic goats from Korean native strain, Capra hircus aegagrus. Small Ruminant Res. 37:57-63   DOI   ScienceOn
13 Robin, N., Laforest, J. P., Lussier, J. G. and Guibault, L. A. 1994. Induction of estrus with intramuscular injections of GnRH or PMSG in lactating goats (Capra hircus) primed with a progestagen during seasonal anestrus. Theriogenology 42:107-116   DOI   ScienceOn
14 Baril, G., Casamitjana, P., Perrin, J. and Valle, J. C. 1988. Embryo production, freezing and transfer in Angora, Alpine and Saanen goats. Proceedings of the 4th Meeting European Embryo Transfer Association (Lyon), p. 67-93
15 Greyling, J. P. C. and Van Niekerk, C. H. 1991. Different synchronization techniques in Boar goat does outside the normal breeding season. Small Ruminant Res. 5:233-243   DOI   ScienceOn
16 Puls-Kleingeld, M., Yuswiati, E., Nowshari, M. A., Beckers, J. F. and Holtz, W. 1991. The effect of FSH/LH ratio and treatment schedule on the superovulatory response in goats, J. Reprod. Fertil. Suppl. 43:308
17 Lee, W. K., Han, Y. M., Shin, S. T., Lee, D. H., Yoo, O. J. and Lee, K. K. 1997. In vitro development of DNA-injected embryos co-culture with goat oviduct epithelial cells in Korean native goat. Theriogenology 47:1115-1123   DOI   ScienceOn