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A Case of Adenocarcinoma Ex Pleomorphic Adenoma with Tumor Thrombus of Submandibular Gland  

Kwon, Chul (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University)
Park, Choel-Eon (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University)
Shin, Il-Ho (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University)
Eun, Young-Gyu (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Sungkyunkwan University, Masan Samsung Hospital)
Kwon, Kee-Hwan (Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University)
Publication Information
Korean Journal of Head & Neck Oncology / v.26, no.2, 2010 , pp. 216-220 More about this Journal
Abstract
Carcinoma ex pleomorphic adenoma is rare, aggressive, poorly understood malignancy that occurs in the salivary glands. The patient was 70-year-old male presenting ovoid elevated submandibular mass that has been present for 30 years and rapid growing for 6 months. The initial cytologic finding by fine needle aspiration biopsy showed highly malignant cells and the radiologic finding revealed a $3.6{\times}3.7{\times}4.8cm$ sized mass with cervical lymphadenopathy. After wide excision of submandibular gland and modified radical neck dissection, the histologic examination revealed that tumor was composed partly of a benign pleomorphic adenoma and partly of an adenocarcinoma component with areas of calcification and frequent angiolymphatic invasion. We present a rare case of adenocarcinoma ex pleomorphic adenoma with tumor thrombus in the submandibular gland.
Keywords
Carcinoma ex pleomorphic adenoma; Submandibular gland; Tumor thrombus;
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