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Patholgic Finding and Surgical Consideration in Micropapillary Carcinoma of the Thyroid  

Lee, Hyun-Chul (Department of General Surgery, College of Medicine, Inje University, Busan Paik Hospital)
Kim, Woon-Won (Department of General Surgery, College of Medicine, Dongrae Paik Hospital)
Oh, Sang-Hoon (Department of General Surgery, College of Medicine, Dongrae Paik Hospital)
Kim, Sang-Hyo (Department of General Surgery, College of Medicine, Inje University, Busan Paik Hospital)
Publication Information
Korean Journal of Head & Neck Oncology / v.24, no.2, 2008 , pp. 189-193 More about this Journal
Abstract
Objectives：The incidence of micropapillary thyroid carcinoma(MPC) which is very good prognosis is increasing due to ultrasonography and accurate fine neede aspiration cytology. MPC defined papillary thyroid carcinoma below 1cm. According to the size, histophaothogic feature is different, lymph node metastasis and capsular invasion occur occasionally. So, we consider different treatment according to the size of MPC. Matrials and Methods：We reviewed and analyzed the record of 216 MPC patients operated at department of general surgery Busan Paik Hospital since 1995 January to 2005 Desember retrospectively. Result：The sex ratio was 1：9.29(male；21, female；195). Total thyroidectomy 20cases(9.3%), subtotal thyroidectomy 141cases(65%), lobectomy 52cases(24%), completion operation 3cases(1.4%) were done. Combined diseases were follicular carcinoma 4cases, follicular adenoma 11cases, thyroiditis 46cases, nodular hyperplasia 44cases. Lymph node metastasis 56cases and capsular invasion 56cases were presented. Group A(<5mm) was 53cases, group B(5-10mm) was 163cases. Group B showed higher lymph node metastasis and capsular invasion(P<0.05). Multiple carcinoma Showed higher capsular invasion than single carcinoma (P<0.05). Complications were post operative bleeding 1case, husky voice 1case, hypocalcemia 1case. Conclusion：We can consider more extensive operation in 5-10mm of MPC patients.
Keywords
Micropapillary thyroid carcinoma; Lymph node metastasis; Capsular invasion;
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1 Noguchi S, Noguchi A, Mirakami N. Papillary carcinoma of the thyroid. Developing patterns of metastases. Cancer. 1970;26:1053-1060   DOI   ScienceOn
2 Kasai N, Sakamoto A. New subgrouping of small thyroid carcinoma. Cancer. 1987;47:1767-1770
3 Barbaro D, Simit U, Meucci G, Lapi P, Orsini P, Pasquini C. Thyroid papillary cancers: microcarcinoma and carcinoma, incidental cancers and non-incidental cancers are they different disease? Clinical Endoclinology. 2005;63:577-581   DOI   ScienceOn
4 Carcangiu ML, Zampi G, Rosai J. A study its many morphologic expressions and clinical correlates. Pathol Annu. 1985;20:1-44
5 Gardner RE, Tuttle RM, Burman KD, Haddady S, Truman C, Sparling YH, et al. Prognostic importance of vascular invasion in papillary thyroid carcinoma. Arch Otolaryngol Head nad Neck Surg. 2000;126:309-312   DOI
6 Ito J, Noguchi S, Murakami N, Nogchi A. Factors affecting the prognosis of patients with carcinoma the thyroid . Surg Gynecol Obstet. 1980;150:539-544
7 Farrar WB, Cooperman M, James AG. Surgical management of papillary and follicular carcinoma of the thyroid. Ann Surg. 1980;192:701-704   DOI   ScienceOn
8 Bhattacharya N, Fried MP. Assessment of the morbidity and complications of total thyroidectomy. Arch Otolarygol Head Neck Surg. 2002;128:1447-1462
9 Baudin E, Travagli JP, Ropers J, Mancusi F, Bruno-Bossio G, Caillou B, et al. Microcarcinoma of the thyroid gland. Gustave Roussy Institute experience. Cancer. 1998;83:553-59   DOI   ScienceOn
10 Pearce EN, Braverman LE. Papillary thyroid microcarcinoma outcomes and implications for treatment. J Clin Endocrinol Metab. 2004;89:3710-3712   DOI
11 Iwao S, Akio Y, Akira S, Mitsuyasu K, Yoshihide F. Clinicopathologic and immunohistochemimical studies of papillary thyroid microcarcinoma presenting with cervical lymphadenopathy. World J Surg. 1998;22:731-737   DOI
12 Hay ID, Grant CS, Van Heerden JA, Goellner JR, Ebersold JR, Bergstralh EJ. Papillary thyroid microcarcinoma; a study of 535 cases observed in a 50-year period. Surg. 1992;112:1139-1147
13 Appetecchia M, Scarcello G, Pucci E, Procaccini A. Outcome after treatment of papillary thyroid carcinoma. J Exp Clin Cancer Res 2002;21:159-164
14 Dounohue JH, Goldfien SD, Miller TR, Abele JS, Clark OH. Do the prognosis of papillary and follicular thyroid carcinomas differ? Am J Surg. 1984;148:168-173   DOI   ScienceOn
15 Salvatdori B, Del BO R, Pilotti S, Grassi M, Cusumoano F. Occult papillary carcinoma of the thyroid; questionable entity. Eur J Cancer. 1993;29:1817-1820   DOI   ScienceOn
16 Katoh R, Sasaki J, Kurihara H, Suzuki K, Iida Y, Kawaoi A. Multiple thyroid involvement in papillary thyroid carcinoma: a clincopathologic study of 105 consecutive patients. Cancer. 1992; 70:1585-1590   DOI   ScienceOn
17 Sampson RJ, Wootner LB, Bahn RC, Kurland LT. Occult thyroid carcinoma Olmsted County, Minnesota; pevalence at autopsy compared with that Hiroshima and Nagasaki, Japan. Cancer. 1974;34:2072-2076   DOI   ScienceOn
18 Jorda M, Gonzalez CF, mora J, Herrero-Zapatero A, Oral C, Galera H. Prognostic factors in follicular carcinoma of thyroid. Arch Pathol Lab Med. 1993;117:631-635
19 Attie JN, Moskowits GW, Margoileff D, levy LM. Feasibility of total thyroidectomy in treatment of thyroid carcinoma. Am J Surg. 1979;138:555-560   DOI   ScienceOn
20 Pellegriti G, Scollo C, Lummera G, Regallbuto C, Vigneri R, Belfiore A. Clinical behavior and out come of papillaty thyroid cancers smaller than 1.5cm in diameter: study of 299 cases. J Clin Endocrinol Metab. 2004;89:3713-3720   DOI
21 Block M. Management of carcinoma of the thyroid. Ann Surg 1977;185:133-144   DOI   ScienceOn
22 Kim JH, Kim JH. Papillary microcarcinoma of the thyroid. Korean J Surg. 2001;61:485-490
23 Hazard JB. Small papillary carcinoma of thyroid: a study with special reference to so-called nonencapsulated sclerosing tumor. Lab Invest, 1960:9-86
24 Hubert JP, Kierman W, Beahrs OH, McConahey WM, Wooln LB. Occult papillary carcinoma of thyroid. Arch Surg. 1980;115: 394-398
25 Chow SM , Law SCK, Chan JCK, Yau S, Lau WH. Papillary microcarcinoma of the thyroid-Prognostic significance of lymph node metastasis and multifocality. Cancer. 2003;98:31-40   DOI   ScienceOn
26 Clark OH. Total thyroidectomy. Ann Surg. 1982;196:361-370   DOI   ScienceOn
27 Nagouchi S, Yamashita M, Murakami N, nakayama I, Toda M, Kawamoto H. Small carcinomas of the thyroid. A long term follow- up of 876 patients. Arch Surg. 1996;13:187-191