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A Case of Extramedullary Plasmacytoma in Palatine Tonsil Achieved Complete Remission by Radiotherapy  

Lee Jung-Hwa (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Kim Ki-Seong (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Kim Hyo-Jung (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Park Hee-Chul (Department of Radiation Oncology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Bae Hoon-Sik (Department of Radiation Oncology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Ha Jun-Wook (Department of Internal Medicine, Hyewon St. Marry's Hospital)
Zang Dae-Young (Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine)
Publication Information
Korean Journal of Head & Neck Oncology / v.21, no.2, 2005 , pp. 165-169 More about this Journal
Abstract
Extramedullary plasmacytoma(EMP) is a rare tumor that originates as a clone of malignant transformed plasma cells. EMPs make up 4% of all plasma cell tumors and 90% of EMP cases occur in the head and neck area. The diagnosis of EMP is based on the morphologic and immunophenotypical finding of a localized collection of monoclonal plasma cells in the absence of plasma cell proliferation elsewhere. Patients with EMP can be treated by surgery or radiotherapy alone or in combination. EMP has good prognosis but long-term follow-up is critical because local recurrence or systemic progression to multiple myeloma may develop more than 30 years after the initial diagnosis of EMP. We report a case of EMP in palatine tonsil of 21-year old man who was treated successfully by radiotherapy alone.
Keywords
Extramedullary plasmacytoma; Palatine tonsil; Radiotherapy;
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1 Alexiou C, Kau RJ, Dietzfelbinger H, et al: Extramedullary plasmacytoma. Tumor occurrence and therapeutic concepts. Cancer. 1999;85:2305-2314   DOI   PUBMED   ScienceOn
2 홍석찬. 이송원. 장 철. 신현수: 비중격으로부터 기원한 골수외 형질세포종 1예. 한이인지. 2003;46:81-84
3 Kost KM: Plasmacytomas of the larynx. J Otolaryngol. 1990; 19:141-146
4 Hellwig CA: Extramedullary plasma cell tumors as observed in various locations. Arch Path. 1943;36:96-111
5 Rubin J, Johnson IT, Killeen R, Killeen R, Barnes L: Extramedullary plasmacytoma of the thyroid associated with a serum monoclonal gammopathy. Arch Otolaryngol Head Neck Surg. 1990;116:855-859   DOI   ScienceOn
6 Kapadia SB, Desai U, Cheng VS: Extramedullary plasmacytoma of the head and neck: A clinicopathologic study of 20 cases. Medicine. 1982;61:317-329   DOI
7 Wax MK, Yun JY, Omar O: Extramedullary plasmacytomas of the head and neck. Arch Otolaryngol Head Neck Surg. 109:877-85, 1993   DOI
8 Batsakis JG, Fries GT, Goldman RT, Karlsberg RT, Arbor A: Upper respiratory tract plasmacytoma. Arch otolaryngol. 1964; 79:613-618   DOI
9 Willis RA: Principles of pathology, 2nd ed. p.554, London, Butterworth, 1961
10 신옥란 . 박경신 . 이연수. 정은선 . 김선무. 김병기: 대장에 발생한 원발성 골수외 형질세포종. 대한병리학회지. 2001: 35:80-82
11 Barat M, Sciubba JJ: Pathologic quiz case 2. Arch Otolaryngol Head Neck Surg. 1984;110:820-823   DOI
12 Dimopoulos MA, Kiamouris C: Solitary plasmacytoma of bone and extramedullary plasmacytoma. Hematol Oneol Clin North Am. 1999;13:1249-1257   DOI   ScienceOn
13 Turley H, Jones M, Erber W, Mayne K, de Waele M, Gatter K: VS38: A new monoclonal antibody for detecting plasma cell differentiation in routine sections. J Clin Pathol. 1994;47:418-422   DOI   ScienceOn
14 장일환. 박정수. 김향복. 이법영: 편도 및 아데노이드에 발생한 골수외 형질세포종 1예. 한이인지. 2001;44:1123-1126
15 Sulzner SE, Amdur RJ, Weider DJ: Extramedullary plasmacytoma of the head and neck. Am J Otolaryngol. 1998;19:203-208   DOI   ScienceOn
16 신익순, 김영봉, 홍정훈, 조태권: 편도에 발생한 골수외 형질세포종 l례. 한이인지. 1994;37:1342-1346
17 Wiltshaw E: The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine. 1976;55:217-238   DOI   PUBMED   ScienceOn
18 설기엽. 신상근. 이형주. 손경락: 골수외 형질세포종 2례. 한이인지, 1993;36:1356-1361