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A Case of Osteosarcoma of the Mandible  

Kim Chan-Jong (Department of Otolaryngology, University of Ulsan College of Medicine)
Lee Jae-Dong (Department of Otolaryngology, Masan Samsung Medical Cener)
Nam Soon-Yuhl (Department of Otolaryngology, University of Ulsan College of Medicine)
Publication Information
Korean Journal of Head & Neck Oncology / v.19, no.2, 2003 , pp. 179-183 More about this Journal
Abstract
Osteosarcoma is one of the most frequently occurring malignant bone tumor except for multiple myeloma. However, osteosarcoma of the mandible is rare and aggressive malignancy constituting about 5% to 13% of all cases of skeletal osteosarcoma. The authors experienced a case of osteosarcoma of the mandible in a 31-years old male patient. He visited our outpatient clinic with painless mass of the cheek. On the basis of the clinical and imaging findings, the differential diagnosis included giant cell tumor, histiocytosis and malignant bone tumor. In the first operation, the mass of the mandible was excised. Intraoperative microscopic examination of a frozen section did not yield a diagnosis: however, the final definitive histologic examination revealed osteoblastic osteosarcoma. After 15days, wide excision with hemimandibulectomy was completed followed by postoperative radiotherapy and chemotherapy. With our experience, we report the progression of diagnosis and management for mandibular osteosrcoma.
Keywords
Osteosarcoma; Mandible; Osteoblast;
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1 Mardinger O, Givol N, Tahni YP, Taicher S : Osteosarcoma of the jaw : The Chaim Sheba medical center experience. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 ; 91 : 445-451   DOI   ScienceOn
2 Slow IN, Stern D, Friedman EW : Osteogenic sarcoma arising in preexisting fibrous dysplasia: Report of case. J Oral Surg. 1971 ; 29 : 126-129   PUBMED
3 Eliber FR, Rosen G : Adjuvant chemotherapy of osteosarcoma. Semin Oncol. 1989 ; 16 : 312-323
4 Mark KG, Sercarz JA, Tran L, Dodd LG, Selch M, Calcaterr TC : Osteogenic sarcoma of the head and neck : the UCLA experience. Arch Otolaryngol Head Neck Surg. 1991 ; 117 : 761-766   DOI   ScienceOn
5 Rosen G, Marcove RC, Capparros B : Primary osteogenic sarcoma : the rationalefor preoperative chemotherapy and delayed surgery. Cancer. 1979 ; 43 : 2163-2177   DOI   ScienceOn
6 Koh YC, Choi HC : A case of osteosarcoma arising from left maxilla. Korean J Otolaryngol. 1967 ; 10 : 103-105
7 Dahlin DC : Bone tumors. 3rd ed. Springfield: Charles E. Thomas. 1978 : 226-273
8 Bertoni F, Dallera P, Bacchini P, Marchetti C, Campobassi A : The Instituto Rizzoli-Beretta experience with osteosarcoma the jaw. Cancer. 1991 ; 68 : 1555-1563   DOI   ScienceOn
9 Garrington GE, Scofield HH, Cornyn J, Hooker SP : Osteosarcoma of the jaws : analysis of56 cases. Cancer. 1967 ; 20 : 77-91   DOI   ScienceOn
10 Lee SD, Hong RB : Osteogenic sarcoma of the maxilla. Korean J Otolaryngol. 1975 ; 20 : 33-36
11 Zorzan G, Tullio A, Bertolini F, Sesenna E : Osteosarcoma of the mandibular condyle : case report. J Oral Maxillofacial Surg. 2001 ; 59 : 574-577   DOI   ScienceOn
12 Delgado R, Maafs E, Alfeiran A, et al : Osteosarcoma of the jaw. Head Neck. 1994; 16 : 246-252   DOI   ScienceOn
13 Chambers RG, Mahoney WD : Osteogenic sarcoma of the mandibke : current management. Am J Clic Pathol. 1970 ; 54 : 625-636   DOI
14 Undqvist C, Teppo L, Sane J, Holmstrom T, Wolf J : Osteosarcoma of the mandible. J Oral Maxillofacial Surg. 1986 ; 44 : 759-764   DOI   ScienceOn
15 Caron AS, Hajdu SI, Strong EW : Osteogenic sarcoma of the facial and cranial bones: a review of forty-three cases. Am J Surg. 1971 ; 122 : 719-725   DOI   ScienceOn
16 Arlen M : Radiation induced sarcoma of bone. Cancer. 1971 ; 28 : 1087-1090   DOI   ScienceOn
17 Abubaker AO, Braun TW, Sotereanos GC, Erickson ER : Osteosarcoma of the mandibular condyle. J Oral Maxillofacial Surg. 1986 ; 44 : 126-131   DOI   ScienceOn
18 Clark L, Unni KK, Dahlin DC : Osteosarcoma of the jaw. Cancer. 1983 ; 51 : 2311-2316   DOI   ScienceOn
19 Aymond AK, Ayala A, Spires J, et al : Osteosarcoma of head and neck. LAB Invest. 1989 ; 60 : 76A