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http://dx.doi.org/10.14400/JDC.2019.17.5.399

Effects of Aerobic Exercise and Chrysin Supplementation on Macrophage Infiltration and Lipolysis Genes of High-Fat Diet Mice  

Choi, Do-Yourl (Center for Sport Science)
Lee, Young-Ran (Center for Sport Science)
Publication Information
Journal of Digital Convergence / v.17, no.5, 2019 , pp. 399-405 More about this Journal
Abstract
This study was investigated the effect of aerobic exercise and chrysin supplementation on macrophage infiltration and lipolysis in high-fat diet mice. To accomplish the purpose of this study, C57BL/6 mice were fed high fat diet(60% fat diet) during experimental period. The animals were divided into 4 groups; NC (normal diet control, n=5), HC (high fat diet control, n=5), Hch(high fat diet with chrysin, n=5), and HME (high fat diet with aerobic exercise training, n=5). Exercise training was performed for 16 weeks on a treadmill running. As a result, macrophage marker, F480 and CD11c were significantly decreased in HME comparison with HD and Hch. Also, M2 macrophage marker CD11c, and lipolysis marker PRDM were significantly increased in HME compared with HC and Hch These findings suggest that regular aerobic exercise has beneficial effects to inhibit macrophage infiltration in high fat diet mice.
Keywords
Exercise; Honey; Macrophages; Lipolysis; Diet; High-fat;
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