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Effects of Vanadium Water on Cancer-related Fatigue of Non Advanced Thyroid Cancer Patients: Randomized, Three armed, Triple Blinded Controlled Trial  

Zheng, Hong-Mei (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University)
Kim, Dong-Hee (Dept. of Oriental Pathology, College of Oriental Medicine, Daejeon University)
Lee, Suk-Hoon (Dept. of Statistics, Graduate School Chungnam National University)
Kim, Kyung-Soon (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University)
Yoo, Hwa-Seung (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University)
Publication Information
Journal of Haehwa Medicine / v.20, no.2, 2012 , pp. 79-89 More about this Journal
Abstract
Objective : This study was conducted to evaluate of efficacy and safety of Vanadium Water (VW) on Cancer related Fatigue of Non-advanced Cancer Patients. Methods : Experimental Group Administration. Participants in treatment group consumed three 500 ml/bottle bottles of Jeju Island's VW, which contains 40.2 ${\mu}g/L$ of vanadium, three times a day (morning, afternoon, evening) for 4 weeks (28 days) without any additional treatments for fatigue improvement. The control group participants consumed three 500 ml/bottle bottles of ordinary water (0 ${\mu}g/L$ of vanadium) three times a day for the same period of time without any additional treatments for fatigue improvement. Results : After 4 weeks of VW consumption, total score of Revised Piper Fatigue Scale (RPFS) was reduced 30% and basal score after Fisher's Exact Test resulted statistical borderline significance (p=0.0799) and result of t-test of comparison between two groups' RPFS total score and fatigue cognitive/mood changes resulted statistical significance (p=0.0112). In detail, only 36.4% of control group (N=11) showed improvement while 77.8% of treatment group (N=9) showed fatigue improvement and thyroid hormone level changes. No other lab measures indicated any significant differences between two groups. Conclusion : Daily consumption of 1.5 L of Vanadium water for 4 weeks showed improvement of non-advanced cancer patients' fatigue.
Keywords
Chronic fatigue; Vanadium Water; Thyroid cancer; Revised Piper Fatigue Scale; Randomized Controlled Trial;
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