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http://dx.doi.org/10.7465/jkdi.2015.26.3.677

Major gene identification for SREBPs and FABP4 gene which are associated with fatty acid composition of Korean cattle  

Lee, Jae-Young (Department of Statistics, Yeungnam University)
Jang, Ji-Eun (Department of Statistics, Yeungnam University)
Oh, Dong-Yep (Gyeongsangbuk-Do Livestock Research Institute)
Publication Information
Journal of the Korean Data and Information Science Society / v.26, no.3, 2015 , pp. 677-685 More about this Journal
Abstract
Disease of human and economic traits of livestocks are affected a lot by gene combination effect rather than a single gene effect. In this study, we used SNPHarvester method that supplement existing method in order to investigate the interaction of these genes. The used genes are SREBPs (g.3270+10274 C>T, g.13544 T>C) and FABP4 (g.2634+1018 A>T, g.2988 A>G, g.3690 G>A, g.3710 G>C, g.3977-325 T>C, g.4221 A>G) that are closely related to the fatty acid composition affecting the meatiness of Korean cattle. The economic traits which are used are oleic acid (C18:1), monounsaturated fatty acid (MUFA), marbling score (MS). First, we have utilized the SNPHarvester method in order to find excellent gene combination, and then used the multifactor dimensionality reduction method in order to identify excellent genotype in gene combination.
Keywords
Gene combination; genotype; multifactor dimensionality reduction; SNPHarvester;
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Times Cited By KSCI : 6  (Citation Analysis)
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