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Hyperlipidemia effect of garlic using mean difference of meta analysis  

Yun, A-Reum (Department of Information and Statistics, Duksung Womens University)
Choi, Ki-Heon (Department of Information and Statistics, Duksung Womens University)
Publication Information
Journal of the Korean Data and Information Science Society / v.22, no.3, 2011 , pp. 413-421 More about this Journal
Abstract
The present study was carried out to summarize the effect of garlic in the hyperlipidemia rats by meta-analysis related studies. The association measure to test effect of garlic was the mean difference (MD). In this particular fixed-effect model of mean difference, body weight, liver weight, kidney weight and heart weight were significantly decreased (p < 0.05). Also, blood glucose, plasma total cholesterol, plasma triglycerides, LDL-cholesterol, liver cholesterol, liver triglycerides were significantly decreased. HDL-cholesterol was significantly increased. In this case of heterogeneous variable, random effect model was applied. In this model, liver weight, blood glucose, plasma total cholesterol, plasma triglycerides, LDL-cholesterol, liver cholesterol, liver triglycerides were significantly decreased. HDL-cholesterol was significantly increased. According to the meta-regression analysis, duration of injection was significantly for kidney weight, testis weight, plasma total cholesterol, plasma triglycerides, HDL-cholesterol, LDLcholesterol, liver cholesterol, liver triglycerides.
Keywords
Garlic; mean difference; meta-regression analysis;
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