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http://dx.doi.org/10.5946/ce.2011.44.2.129

A Case of Oral-contraceptive Related Ischemic Colitis in Young Woman  

Seon, Choon-Sik (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Park, Young-Sook (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Park, Se-Hwan (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Ryu, Sang-Ryol (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Jo, Yun-Ju (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Kim, Seong-Hwan (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Son, Byoung-Kwan (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Ahn, Sang-Bong (Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine)
Publication Information
Clinical Endoscopy / v.44, no.2, 2011 , pp. 129-132 More about this Journal
Abstract
Ischemic colitis is generally considered a disease of the elderly. The causes of ischemic colitis include low-flow states due to cardiac dysfunction or hypovolemia and certain medications including estrogen. Here we report a case of ischemic colitis in a 26-year-old woman. She had no specific medical history except taking oral-contraceptives for a long time. The mechanism of estrogen-induced ischemic colitis is not clearly understood. But we recommend that oral-contraceptives should be considered as a cause of ischemic colitis in young women.
Keywords
Ischemic colitis; Oral contraceptives;
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1 Gandhi SK, Hanson MM, Vernava AM, Kaminski DL, Longo WE. Ischemic colitis. Dis Colon Rectum 1996;39:88-100.   DOI   ScienceOn
2 Green BT, Tendler DA. Ischemic colitis: a clinical review. South Med J 2005;98:217-222.   DOI   ScienceOn
3 Elder K, Lashner BA, Al Solaiman F. Clinical approach to colonic ischemia. Cleve Clin J Med 2009;76:401-409.   DOI   ScienceOn
4 Binns JC, Isaacson P. Age-related changes in the colonic blood supply: their relevance to ischaemic colitis. Gut 1978;19:384-390.   DOI   ScienceOn
5 Frossard JL, Spahr L, Queneau PE, Armenian B, Brüdler MA, Hadengue A. Ischemic colitis during pregnancy and contraceptive medication. Digestion 2001;64:125-127.   DOI   ScienceOn
6 Cushman M, Kuller LH, Prentice R, et al. Estrogen plus progestin and risk of venous thrombosis. JAMA 2004;292:1573-1580.   DOI   ScienceOn
7 Tyler ET. Oral contraception and venous thrombosis. JAMA 1963; 185:131-132.   DOI   ScienceOn
8 Martinelli I, Mannucci PM, De Stefano V, et al. Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families. Blood 1998;92:2353-2358.
9 Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996;88:3698-3703.
10 Koster T, Rosendaal FR, de Ronde H, Briet E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 1993;342:1503-1506.   DOI   ScienceOn
11 Meijers JC, Middeldorp S, Tekelenburg W, et al. Increased fibrinolytic activity during use of oral contraceptives is counteracted by an enhanced factor XI-independent down regulation of fibrinolysis: a randomized cross-over study of two low-dose oral contraceptives. Thromb Haemost 2000;84:9-14.
12 Tchaikovski SN, Rosing J. Mechanisms of estrogen-induced venous thromboembolism. Thromb Res 2010;126:5-11.   DOI   ScienceOn
13 de Visser MC, van Hylckama Vlieg A, Tans G, et al. Determinants of the APTT- and ETP-based APC sensitivity tests. J Thromb Haemost 2005; 3:1488-1494.   DOI   ScienceOn
14 Odlind V, Milsom I, Persson I, Victor A. Can changes in sex hormone binding globulin predict the risk of venous thromboembolism with com-bined oral contraceptive pills? Acta Obstet Gynecol Scand 2002;81: 482-490.
15 Kemmeren JM, Algra A, Meijers JC, et al. Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor V Leiden mutation: a randomized trial. Blood 2004;103:927-933.
16 Pomp ER, le Cessie S, Rosendaal FR, Doggen CJ. Risk of venous th-rombosis: obesity and its joint effect with oral contraceptive use and prothrombotic mutations. Br J Haematol 2007;139:289-296.   DOI   ScienceOn
17 Brandt LJ, Feuerstadt P, Blaszka MC. Anatomic patterns, patient characteristics, and clinical outcomes in ischemic colitis: a study of 313 cases supported by histology. Am J Gastroenterol 2010;105:2245-2252.   DOI   ScienceOn
18 Carpenter HA, Talley NJ. The importance of clinicopathological correl-ation in the diagnosis of inflammatory conditions of the colon: histolo-gical patterns with clinical implications. Am J Gastroenterol 2000;95:878-896.   DOI   ScienceOn
19 Paterno F, McGillicuddy EA, Schuster KM, Longo WE. Ischemic colitis: risk factors for eventual surgery. Am J Surg 2010;200:646-650.   DOI   ScienceOn
20 Yoon SM. Ischemic colitis: how can it be beneficial? Paper presented at: The 2nd Endofest-Korea; 2011 Mar 26; Seoul, Korea.