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De Novo Submucosal Colorectal Cancer in a 3 mm Sessile Polyp  

Koo, So-My (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Kim, Jin-Oh (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Kim, Hyun-Gun (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Lee, Tae-Hee (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Jeon, Seong-Ran (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Jin, So-Young (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Lee, Joon-Seong (Institute for Digestive Research, Soonchunhyang University College of Medicine)
Publication Information
Clinical Endoscopy / v.42, no.2, 2011 , pp. 109-112 More about this Journal
Abstract
The majority of colorectal carcinomas (95~100%) are thought to arise from adenomas. Yet colorectal carcinomas may rarely arise de novo. The popular definition of de novo carcinoma is that the lesion should consist exclusively of a carcinoma histologically and contain no adenomatous elements. Without an adenoma-carcinoma sequence, de novo carcinomas have a much higher rate of submucosal invasion, despite their small size. Their speed of growth is thought to be rapid. Some studies have shown that de novo carcinomas might arise as a macroscopically flat or depressed lesion, rather than a protruded one. However, the typical macroscopic findings of de novo carcinomas have not been established. They might be variable macroscopically and include a protruded type. We report a case of de novo colorectal carcinoma that invaded the submucosal layer involving a minute sessile polyp only 3 mm in diameter, which was removed by endoscopic mucosal resection.
Keywords
Submucosal invasive colorectal cancer; Early colorectal carcinoma; Minute sessile polyp; De novo carcinoma;
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