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http://dx.doi.org/10.3345/kjp.2016.59.4.174

Usefulness of anterior uveitis as an additional tool for diagnosing incomplete Kawasaki disease  

Lee, Kyu Jin (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Kim, Hyo Jin (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Kim, Min Jae (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Yoon, Ji Hong (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Eun Jung (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Jae Young (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Oh, Jin Hee (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Soon Ju (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Kyung Yil (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Han, Ji Whan (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Publication Information
Clinical and Experimental Pediatrics / v.59, no.4, 2016 , pp. 174-177 More about this Journal
Abstract
Purpose: There are no specific tests for diagnosing Kawasaki disease (KD). Additional diagnostic criteria are needed to prevent the delayed diagnosis of incomplete Kawasaki disease (IKD). This study compared the frequency of coronary artery lesions (CALs) in IKD patients with and without anterior uveitis (AU) and elucidated whether the finding of AU supported the diagnosis of IKD. Methods: This study enrolled patients diagnosed with IKD at The Catholic University of Korea, Uijeongbu St. Mary's Hospital from January 2010 to December 2014. The patients were divided into 2 groups: group 1 included patients with IKD having AU; and group 2 included patients with IKD without AU. We analyzed the demographic and clinical data (age, gender, duration of fever, and the number of diagnostic criteria), laboratory results, and echocardiographic findings. Results: Of 111 patients with IKD, 41 had uveitis (36.98%, group 1) and 70 did not (63.02%, group 2). Patients in group 1 had received a diagnosis and treatment earlier, and had fewer CALs (3 of 41, 1.7%) than those in group 2 (20 of 70, 28.5%) (P=0.008). All 3 patients with CALs in group 1 had coronary dilatation, while patients with CALs in group 2 had CALs ranging from coronary dilatation to giant aneurysm. Conclusion: The diagnosis of IKD is challenging but can be supported by the presence of features such as AU. Group 1 had a lower risk of coronary artery disease than group 2. Therefore, the presence of AU is helpful in the early diagnosis and treatment of IKD and can be used as an additional diagnostic tool.
Keywords
Kawasaki disease; Anterior uveitis; Delayed diagnosis; Coronary artery;
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