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http://dx.doi.org/10.3345/kjp.2012.55.6.202

Epidemiology of Kawasaki disease in infants 3 months of age and younger  

Lee, Eun Jung (Department of Pediatrics, The Catholic University of Korea School of Medicine)
Park, Yong Won (Department of Pediatrics, Inje University College of Medicine)
Hong, Young Mi (Department of Pediatrics, Ewha Womans University School of Medicine)
Lee, Joon Sung (Department of Pediatrics, The Catholic University of Korea School of Medicine)
Han, Ji Whan (Department of Pediatrics, The Catholic University of Korea School of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.55, no.6, 2012 , pp. 202-205 More about this Journal
Abstract
Purpose: This study investigated the epidemiology of Kawasaki disease (KD) in infants ${\leq}3$-month-old. Methods: To study the epidemiology of KD in Korea, data for 27,851 KD patients were collected on a 3-year basis between 2000 and 2008 in a retrospective survey. From this, data for 609 KD patients ${\leq}3$-month-old were analyzed and compared with the data for KD patients >3-month-old. Results: The 609 KD patients ${\leq}3$-month-old (385 males and 224 females) constituted 2.2% of the KD patients. They included 25 infants <1-month-old, 198 infants ${\leq}1$- to 2-month-old, and 386 infants >2- and 3-months-old. The ratio of males to females was 1.72:1. The incidence of coronary artery (CA) dilatation (19.9% vs. 18.7%) and CA aneurysms (3.4% vs. 2.6%) detected by echocardiography did not differ significantly between patients with KD younger and older than 3-month-old. Conclusion: Compared with the data for the KD patients >3-month-old, the data for the 609 patients ${\leq}3$-month-old did not show a significantly higher incidence of CA dilatation or CA aneurysms.
Keywords
Kawasaki disease; Coronary artery dilatation; Coronary aneurysm; Epidemiology; Infant;
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1 Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Arerugi 1967;16:178-222.
2 Melish ME. Kawasaki syndrome. Pediatr Rev 1996;17:153-62.   DOI   ScienceOn
3 Rowley AH, Shulman ST. Kawasaki syndrome. Pediatr Clin North Am 1999;46:313-29.   DOI   ScienceOn
4 Burns JC, Wiggins JW Jr, Toews WH, Newburger JW, Leung DY, Wilson H, et al. Clinical spectrum of Kawasaki disease in infants younger than 6 months of age. J Pediatr 1986;109:759-63.   DOI
5 Chang FY, Hwang B, Chen SJ, Lee PC, Meng CC, Lu JH. Characteristics of Kawasaki disease in infants younger than six months of age. Pediatr Infect Dis J 2006;25:241-4.   DOI   ScienceOn
6 Yun YS, Kim CH, Kim CH, Tockgo YC, Lee SK, Hong CY. Kawasaki disease in Korea. In: Kato H, editor. Kawasaki disease. New York: Elsevier, 1995:30-3.
7 Park YW, Kim CH, Park IS, Ma JS, Lee SB, Kim CH, et al. Epidemiologic study of Kawasaki disease in Korea, 1994-1996: comparison of previous study in 1991-1993. J Korean Pediatr Soc 1999;42:1255-60.
8 Park YW, Park IS, Kim CH, Ma JS, Lee SB, Kim CH, et al. Epidemiologic study of Kawasaki disease in Korea, 1997-1999: comparison with previous studies during 1991-1996. J Korean Med Sci 2002;17:453-6.
9 Park YW, Han JW, Park IS, Kim CH, Yun YS, Cha SH, et al. Epidemiologic picture of Kawasaki disease in Korea, 2000-2002. Pediatr Int 2005;47:382-7.   DOI   ScienceOn
10 Park YW, Han JW, Park IS, Kim CH, Cha SH, Ma JS, et al. Kawasaki disease in Korea, 2003-2005. Pediatr Infect Dis J 2007;26:821-3.   DOI   ScienceOn
11 Park YW, Han JW, Hong YM, Ma JS, Cha SH, Kwon TC, et al. Epidemiological features of Kawasaki disease in Korea, 2006-2008. Pediatr Int 2011;53:36-9.   DOI   ScienceOn
12 Research Committee on Kawasaki disease. Report of subcommittee on standardization of diagnostic criteria and reporting of coronary artery lesions in Kawasaki disease. Tokyo: Ministry of Health, Labour and Welfare, 1984.
13 Tsuchida S, Yamanaka T, Tsuchida R, Nakamura Y, Yashiro M, Yanagawa H. Epidemiology of infant Kawasaki disease with a report of the youngest neonatal case ever reported in Japan. Acta Paediatr 1996;85: 995-7.   DOI   ScienceOn
14 Iino M, Shiraishi H, Igarashi H, Honma Y, Momoi MY. Case of Kawasaki disease in NICU. Pediatr Int 2003;45:580-3.   DOI   ScienceOn
15 Chuang CH, Hsiao MH, Chiu CH, Huang YC, Lin TY. Kawasaki disease in infants three months of age or younger. J Microbiol Immunol Infect 2006;39:387-91.
16 Stockheim JA, Innocentini N, Shulman ST. Kawasaki disease in older children and adolescents. J Pediatr 2000;137:250-2.   DOI   ScienceOn
17 Park YW, Han JW, Park IS, Kim CH, Cha SH, Ma JS, et al. Clinical and epidemiologic study of Kawasaki disease in children 8 years of age and older. Korean J Pediatr 2005;48:1139-42.
18 Rosenfeld EA, Corydon KE, Shulman ST. Kawasaki disease in infants less than one year of age. J Pediatr 1995;126:524-9.   DOI   ScienceOn
19 Yanagawa H, Nakamura Y, Yashiro M, Ojima T, Tanihara S, Oki I, et al. Results of the nationwide epidemiologic survey of Kawasaki disease in 1995 and 1996 in Japan. Pediatrics 1998;102:E65.   DOI   ScienceOn
20 Park YW, Han JW, Park IS, Kim CH, Cha SH, Ma JS, et al. Epidemiologic study of Kawasaki disease in 6 months old and younger infants. Korean J Pediatr 2008;51:1320-3.   DOI   ScienceOn