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http://dx.doi.org/10.3345/kjp.2010.53.1.106

A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding  

Lee, Jun Seok (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Kim, Kyo Ryung (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Kim, Jeong Tae (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Choi, Min Jung (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Lee, Young Mock (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Kim, Heung Dong (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Lee, Joon Soo (Department of Pediatrics, Severance Children's Hospital Yonsei University College of Medicine)
Kim, Dong Seok (Department of Neurosurgery, Severance Children's Hospital Yonsei University College of Medicine)
Kim, Tae Seong (Department of Pathology, Severance Children's Hospital Yonsei University College of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.53, no.1, 2010 , pp. 106-110 More about this Journal
Abstract
Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.
Keywords
Hippocampus; Cortical dysplasia; Epilepsy; Surgery; MRI;
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