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http://dx.doi.org/10.3345/kjp.2009.52.4.453

Clinical features of acute noroviral gastroenteritis in children : comparison with rotaviral gastroenteritis  

Hwang, Pil-Joo (Department of Pediatrics, College of Medicine, Pochon CHA University)
Kwak, Ji Hee (Department of Pediatrics, College of Medicine, Pochon CHA University)
Lee, Taek Jin (Department of Pediatrics, College of Medicine, Pochon CHA University)
Jeong, Su Jin (Department of Pediatrics, College of Medicine, Pochon CHA University)
Publication Information
Clinical and Experimental Pediatrics / v.52, no.4, 2009 , pp. 453-457 More about this Journal
Abstract
Purpose : Our aim was to describe the clinical features of noroviral gastroenteritis in children. Methods : This study included 22 children with noroviral gastroenteritis, as confirmed by stool RT-PCR, who were admitted to Bundang CHA Hospital between July 2006 and June 2008. Their medical records were reviewed and compared with those of 45 children with rotaviral gastroenteritis. Results : In the norovirus group, 19 (86.4%) children showed vomiting and 21 (95.5%) children showed diarrhea, while all children in the rotaviral group showed both vomiting and diarrhea. The duration of vomiting was not different in the two groups, but mean episodes of vomiting/24 h were higher in the norovirus group than in the rotavirus group. The duration of diarrhea was longer and mean episodes of diarrhea/24 h were higher in the rotavirus group. The Vesikari Scale was not different in the two groups. Frequency and duration of fever did not show a significant difference. Most children in both groups were below 2 years of age. Conclusion : Clinical features of noroviral gastroenteritis were largely similar to those of rotaviral gastroenteritis, but vomiting was more severe in noroviral infection, and diarrhea was more severe and prolonged in rotaviral infection. With regard to noroviral infection, further epidemiologic investigations and preventive efforts are essential.
Keywords
Norovirus; Rotavirus; Children; Gastroenteritis;
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1 Pang XL, Honma S, Nakata S, Vesikari T. Human caliciviruses in acute gastroenteritis of young children in community. J Infect Dis 2000;181:288-94   DOI   ScienceOn
2 Rockx B, de Wit M, Vennema H, Jan V, Erwin B, Yvonne V, Van D, et al. Natural history of human Calicivirus infection: a prospective cohort study. Clin Infect Dis 2002; 35:246-53   DOI   ScienceOn
3 Breese JS, Widdowson M-A, Monroe SS, Glass RI. Foodborne viral gastroenteritis: challenges and opportunities. Clin Infect Dis 2002;35:748-53   DOI   ScienceOn
4 Sack DA, Chowdhury AM, Eusof L, Ali MA, Merson MH, Islan S, et al. Oral rehydration in rotavirus diarrhea: a double blind comparison of sucrose with glucose electrolyte solution. Lancet 1978;2:280-3   DOI   ScienceOn
5 Brown KH, MacLean WC. Nutritional management of acute diarrhea:Ann appraisal of the alternatives. Pediatrics 1984; 73:119-25   PUBMED   ScienceOn
6 Park SE, Kim KH, Kim JH, Shin SH, Oh SH, Lee HJ, et al. Rotavirus vaccine. Korean J Pediatr 2007;50:803-10   ScienceOn
7 Korea centers for disease control and prevention, A outbreak of noroviral diarrhea in Seoul, Epidemiological investigation of infection diseases in Korea annual 18th ed. 2003;111-21
8 de Wit MA, Koopmans MP, Kortbeek LM, Wannet WJ, Vinje J, van Leusden F, et al. Sensor, a population-based cohort study on gastroenteritis in the Netherlands:incidence and etiology. Am J Epidemiol 2001;154:666-74   DOI   ScienceOn
9 Phan TG, Nguyen TA, Kuriowa T, Kuroiwa T, Kaneshi K, Ueda Y, et al. Viral diarrhea in Japanese children: results from a one-year epidemiologic study. Chin Lab 2005;51:183- 91   PUBMED
10 Sakai Y, Nakata S, Homma S, Honma S, Tatsumi M, Numata-Kinoshita K, et al. Clinical severity of Norwalk virus and Sapporo virus gastroenteritis in children in Hokkaido, Japan. Pediatr Infect Dis J 2001;20:849-53   DOI   ScienceOn
11 Irena N, Indre T. Peculiarities of Norovirus and rotavirus infections in hospitalised young children. J Pediatr Gastroenterol Nutr 2008;46:289-92   DOI   ScienceOn
12 Lau CS, Wong DA, Tong LK, Lo JY, Ma AM, Cheng PK, et al. High rate and changing molecular epidemiology pattern of norovirus infections in sporadic cases and outbreaks of gastroenteritis in Hong Kong. J Med Virol 2004;73:113-7   DOI   ScienceOn
13 Snyder JD, Merson MH. The magnitude of the global problem of acute diarrhoeal disease: a review of active surveillance data. Bull WHO 1982; 60: 605-31   PUBMED   ScienceOn
14 Waters A, Coughlan S, Dunford L, Hall WW. Molecular epidemiology of norovirus strains circulating in Ireland from 2003 to 2004. Epidemiol Infect 2006;134:917-25   DOI   ScienceOn
15 Pang XL, Joensuu J, Vesikari T. Human calicivirus-associated sporadic gastroenteritis in Finnish children less than two years of age followed prospectively during a rotavirus vaccine trial. Pediatr Infect Dis J 1999;18:420-6   DOI   ScienceOn
16 Ruuska T, Vesikari T. Rotavirus disease in Finnish children: use of numerical scores for clinical severity of diarrhoeal episodes. Scand. J Infect Dis 1990;22:259-67   DOI   ScienceOn
17 Widdowson M-A, Sulka A, Bulens S, beard R, Chaves S, Hammond R, at al. The role of norovirus(NoV) in outbreaks of foodborne disease-United States, 1991-2000. Emerg Infect Dis 2005;11:95-102   PUBMED   ScienceOn
18 G$\ddot{o}$tz H, Ekdahl K, Lindback J, de Jong B, Hedlund KO, Giesecke J, et al. Clinical spectrum and transmission characteristics of infection with Norwalk-like virus: findings from a large community outbreak in Sweden. Clin Infect Dis 2001;35:748-53   DOI   ScienceOn
19 Lopman BA, Reacher MH, Vipond IB, Sarangi J, Brown DW. Clinical manifestation of norovirus gastroenteritis in health care setting. Clin Infect Dis 2004;39:318-24   DOI   ScienceOn
20 Jee YM. A norovirus food poisoning and laboratory surveillance for viral gastroenteritis in Korea. Health Welfare Forum 2006;118:26-34
21 Nalin DR, Levine MM, Mata L, Cespedes C, William V, Lizano C, et al. Comparison of sucrose with glucose in oral therapy of infant diarrhea. Lancet 1978;2:277-9   PUBMED
22 Takeshi T, Kuzuko N, Shinjiro H, Shuji N, Masatoshi T, Yoshiyuki S, et al. Virological, serological, and clinical features of an outbreak of acute gastroenteritis due to recom binant genogroup II norovirus in an infant home. J Clin Microbiol 2006;44:177-82   DOI   ScienceOn
23 Im IJ, Lee MJ, Chung EH, YU JS, Chang YP, Park WS, et al. Etiology and clinical manifestation of acute gastroenteritis in children. Korean J Pediatr Infect Dis 2006;3:147- 54
24 Kim EJ, Park SH, Song MO, Kim MS, Kim MY, Cheon DS, et al. Genetic distribution of human noroviruses detected from acute gastroenteritis patients in Seoul. Korean J Micro 2008;44:135-9   과학기술학회마을   ScienceOn
25 Marie-Cardine A, Gourlain K, Mouterde O, Castiqnolle N, Hellot MF, Mallet E, et al. Epidemiology of acute viral gastroenteritis in children hospitalized in Rouen, France. Clin infect Dis 2002;34:622-8