Browse > Article

Effect of combined exercise on metabolic bio-marker in overweight and obese children  

Kim, Hyun-Jun (Department of Physical Education, Pusan National University College of Education)
Kim, Tae-Un (Department of Physical Education, Pusan National University College of Education)
Lee, Sangyeoup (Medical Education Unit, Pusan National University School of Medicine and Center for Obesity, Nutrition and Metabolism, Pusan National University Hospital)
Shin, Goon-Soo (Department of Aquatic Sports, Pukyong National University)
Kim, Young-Joo (Department of Family Medicine, Pusan National University Hospital)
Kim, Su-Yung (Department of Pedriatics, Pusan National University School of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.49, no.9, 2006 , pp. 946-951 More about this Journal
Abstract
Purpose : The purpose of this study was to demonstrate the effectiveness of combined exercise for 12 weeks on the adiponectin and obesity related variables in overweight and obese children. Methods : Eighteen children in 5th grade in a certain elementary school in Busan were recruited. They were all overweight or obese children(more than 85 percentile in body mass index). Nine children in the experimental group were given exercises consisting of walking and band resistant training for 12 weeks. Auxological data(including height, weight and body fat mass) and laboratory data (fasting blood sugar, insulin, adiponectin) were checked at baseline and at the 1 week, and at the 4 weeks and 12 weeks stages of their exercise program. Insulin resistance and sensitivity were evaluated indirectly using HOMA index and QUICKI index. Results : Adiponectin gradually decreased until the 4 weeks point and gradually increased thereafter to the starting level at the 12 weeks stage. Body weight, body mass index(BMI) and HOMA index significantly decreased more at the 1 week, 4 weeks, and 12 weeks stages in the experimental group than in the control group. Body fat mass significantly decreased at 12 weeks. The change of insulin was significantly correlated with changes of body weight and BMI. But there was no correlation between changes of adiponectin and changes of insulin. Conclusion : Exercise seems to effect the adiponectin concentration. And it might be assumed that exercise increases the adiponectin concentration if it is continued for long time(may be more than 12 weeks). More studies may be necessary to draw that conclusion.
Keywords
Exercise; Adiponectin; Insulin; Obesity; Overweight; Children;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Kraemer RR, Aboudehen KS, Carruth AK, Durand RT, Acevedo EO, Hebert EP, et al. Adiponectin responses to continuous and progressively intense intermittent exercise. Med Sci Sports Exerc 2003;35:1320-5   DOI   ScienceOn
2 Ascaso JF, Romero P, Real JT, Priego A, Valdecabres C, Carmena R. Insulin resistance quantification by fasting insulin plasma value and HOMA index in a non-diabetic population. Med Clin(Barc) 2001;117:530-3   DOI   ScienceOn
3 Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA 2003;289:1799-804   DOI   ScienceOn
4 Yang WS, Lee WJ, Funahashi T, Tanaka S, Matsuzawa Y, Chao CL, et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001;86:3815-9   DOI
5 Jurimae J, Purge P, Jurimae T. Adiponectin is altered after maximal exercise in highly trained male rowers. Eur J Appl Physiol 2005;93:502-5   DOI
6 Bruce CR, Hawley JA. Improvements in insulin resistance with aerobic exercise training : a lipocentric approach. Med Sci Sports Exere 2004;36:1196-201
7 Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000;20:1595-9   DOI   ScienceOn
8 Wang H, Zhang H, Jia Y, Zhang Z, Craig R, Wang X, Elbein SC. Adiponectin receptor 1 gene(ADIPOR1) as a candidate for type 2 diabetes and insulin resistance. Diabetes 2004;53:2132-6   DOI   ScienceOn
9 Hulver MW, Zheng D, Tanner CJ, Houmard JA, Kraus WE, Slentz CA, et al. Adiponectin is not altered with exercise training despite enhanced insulin action. Am J Physiol Endocrinol Metab 2002;283:E861-5   DOI
10 Reinehr T, Roth C, Menke T, Andler W. Adiponectin before and after weight loss in obese children. J Clin Endocrinol Metab 2004;89:3790-4   DOI
11 Cruz M, Garcia-Macedo R, Garcia-Valerio Y, Gutierrez M, Medina-Navarro R, Duran G, et al. Low adiponectin levels predict type 2 diabetes in Mexican children. Diabetes Care 2004;27:1451-3   DOI   ScienceOn
12 Matsuzawa Y, Funahashi T, Kihara S, Shimomura I. Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol 2004;24:29-33   DOI   ScienceOn
13 Boudou P, Sobngwi E, Mauvais-Jarvis F, Vexiau P, Gautier JF. Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men. Eur J Endocrinol 2003;149:421-4   DOI   ScienceOn
14 Schulze MB, Rimm EB, Shai I, Rifai N, Hu FB. Relationship between adiponectin and glycemic control, blood lipids, and inflammatory markers in men with type 2 diabetes. Diabetes Care 2004;27:1680-7   DOI   ScienceOn
15 Hrebicek J, Janout V, Malincikova J, Horakova D, Cizek L. Detection of insulin resistance by simple quantitative insulin sensitivity check index QUICKI for epidemiological assessment and prevention. J Clin Endocrinol Metab 2002;87:144-7   DOI   ScienceOn
16 Havel PJ. Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol 2002;13:51-9   DOI   ScienceOn