Relationship of serum IL-13 and eotaxin level with airway hyperresponsiveness in children with asthma
![]() |
Park, Eun Young
(Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
Shim, Jung Yeon (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) Yoo, Myung Hwan (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) Kim, Deok Soo (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) Shim, Jae Won (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) Jung, Hye Lim (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) Park, Moon Soo (Department of Pediatrics, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) |
1 | Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, et al. Inter leukin-13 : Central mediator of allergic asthma. Science 1998;282:2258-61 DOI ScienceOn |
2 | Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, et al. Pulmonary expression of interleukin-13 causes inflmmation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clincal Invest 1999;103:779-89 DOI ScienceOn |
3 | Yang M, Hogan SP, Mahalingam S, Pope SM, Zimmermann N, Fulkerson P, et al. Eotaxin-2 and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperreactivity. J Allergy Clin Immunol 2003; 112:935-43 DOI ScienceOn |
4 | Li L, Xia Y, Nguyen A, Lai YH, Feng L, Mosmann TR, et al. Effect of Th2 cytokines on chemokine expression in the lung : IL-13 potently induces eotaxin expression by airway epithelial cells. J Immunol 1999;162:2477-87 |
5 | Pope SM, Brandt EB, Mishra A, Hogan SP, Zimmermann N, Matthaei KI, et al. IL-13 induces eosinophil recruitment into the lung by an IL-5 and eotaxin dependent mechanism. J Allergy Clin Immunol 2001;108:594-601 DOI ScienceOn |
6 | Schmid-Grendelmeier P, Altznauer F, Fischer B, Bizer C, Straumann A, Menz G, et al. Eosinophils express functional IL-13, in eosinophilic inflammatory disease. J Immunol 2002;169:1021-7 DOI |
7 | Min JW, Jang AS, Park SM, Lee JH, Park SW, Park CS. Comparison of plasma eotaxin family level in aspirininduced and aspirin-tolerant asthma patient. Chest 2005;128: 127-32 |
8 | Li J, Saito H, Crawford L, Inman MD, Cyr MM, Denburg JA. Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology 2005;114:386-96 DOI ScienceOn |
9 | Venkayya R, Lam M, Willkom M, Grunig G, Corry DB, Erle DJ. The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells. Am J Respir Cell Mol Biol 2002;26:202-8 DOI ScienceOn |
10 | Chang JY, Shin SA, Oh JW, Lee HB. Crucial factors for bronchial hyperresponsiveness in children with mild asthma. Pediatr Allergy Respir Dis 2005;15:142-9 |
11 | Moore PE, Church TL, Chism DD, Panettieri RA Jr, Shore SA. IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells : a role for ERK. Am J Physiol Lung Cell Mol Physiol 2002;282:847-52 DOI |
12 | Yang G, Volk A, Petley T, Emmell E, Giles-Komar J, Shang X, et al. Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling. Cytokine 2004;28:224-32 DOI ScienceOn |
13 | O'Bryan L, Pinkston P, Kumaraswami V, Vijayan V, Yenokida G, Rosenberg HF, et al. Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia. Infect Immun 2003;71:1337-42 DOI |
14 | Shin SA, Oh JW, Lee HB, Kim NS, Lee HB. Relationship between airway hyperresposiveness and duration of asthma in children. J Asthma Allergy Clin Immunol 2003;23:77-83 |
15 | Matsukura S, Stellato C, Georas SN, Casolaro V, Plitt JR, Miura K, et al. Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. Am J Respir Cell Mol Biol 2001;24:755-61 DOI ScienceOn |
16 | Taube C, Duez C, Cui ZH, Takeda K, Rha YH, Park JW, et al. The role of IL-13 in established allergic airway disease. J Immunol 2002;169:6482-9 DOI |
17 | Hummelshoj T, Bodtger U, Datta P, Malling HJ, Oturai A, Poulsen K, et al. Association between an interleukin-13 promotor polymorphism and atopy. Eur J Immunogenet 2003;30:355-9 DOI ScienceOn |
18 | Walter DM, McIntire JJ, Berry G, McKenzie AN, Donaldson DD, DeKruyff RH, et al. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J Immunol 2001;167:4668-75 DOI |
19 | Jung EM, Kim HS, Kang IJ. A 10 year follow-up childhood asthma : Potential risk factors on persistence of nonspecific bronchial hyperresponsiveness. Pediatr Allergy Respir Dis 2002;12:82-92 |
20 | Zhou G, Zhai Y, Dong X, Zhang X, He F, Zhou K, et al. Haplotype structure and evidence for positive selection at the human IL13 locus. Mol Biol Evol 2004;21:29-35 |
21 | Kim JT. Evaluation of inflammation in childhood asthma; Non-invasive measurement. J Korean Pediatr Soc 2001;44: 334-9 |
22 | Zimmermann N, Hershey GK, Foster PS, Rothenberg ME. Chemokines in asthma : Cooperative interaction between chemokines and IL-13. J Allergy Clin Immunol 2003;111: 227-42 DOI ScienceOn |
23 | The Korean Academy of Pediatric Allergy and Respiratory Disease. The guideline for diagnosis and management of childhood asthma. 2nd ed. Seoul : Sowha Co, 1999:5-87 |
24 | Chai H, Farr RS, Froehlich LA, Mathison DA, McLean JA, Rosenthal RR, et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 1975;56:323- 58 DOI |
25 | Arima K, Umeshita-Suyama R, Sakata Y, Akaiwa M, Mao XQ, Enomoto T, et al. Upregulation of IL-13 concentraion in vivo the IL-13 variant associated with bronchial asthma. J Allergy Clin Immunol 2002;109:980-7 DOI ScienceOn |
![]() |