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Gastric neurofibroma in von Recklinghausen disease : a cause of upper gastrointestinal bleeding  

Kwon, Bo Sang (Department of Pediatrics, Seoul National University College of Medicine)
Shim, Jeong Ok (Department of Pediatrics, Seoul National University College of Medicine)
Seo, Jeong Kee (Department of Pediatrics, Seoul National University College of Medicine)
Yang, Hye Ran (Department of Pediatrics, Seoul National University College of Medicine)
Ko, Jae Sung (Department of Pediatrics, Seoul National University College of Medicine)
Jung, Seong Eun (Department of Surgery, Seoul National University College of Medicine)
Kim, Woo Sun (Department of Radiology, Seoul National University College of Medicine)
Kang, Gyeong Hoon (Department of Pathology, Seoul National University College of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.49, no.2, 2006 , pp. 203-207 More about this Journal
Abstract
Neurofibromatosis type 1 (von Recklinghausen disease, NF1) involves the central and peripheral nervous systems as well as the skin, bone, endocrine, gastrointestinal and vascular systems. The gastrointestinal neurofibroma associated with NF1 has been infrequently reported. We report our experience with a 15-year-old boy who had a gastric plexiform neurofibroma with upper gastrointestinal bleeding and underwent a tumorectomy because of massive upper gastrointestinal bleeding. We conclude that gastrointestinal bleeding and anemia in the setting of NF1 mandates complete endoscopic examination of the digestive tract to rule out neurofibromas. Surgical resection is the standard treatment.
Keywords
Neurofibromatosis; Plexiform neurofibroma; Stomach; Gastrointestinal bleeding;
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