Browse > Article

The Clinical Study on the Neonate Delivered Under the Condition of the Maternal Smoking and Alcohol in Pregnancy  

Kong, Sun Hui (Department of Pediatrics, National Medical Center)
Kim, Soo Yeon (Department of Pediatrics, National Medical Center)
Lee, Ho Jun (Department of Pediatrics, National Medical Center)
Kim, Hak Sung (Department of Pediatrics, National Medical Center)
Lee, Dong Woo (Department of Pediatrics, National Medical Center)
Kim, Jae Yoon (Department of Pediatrics, National Medical Center)
Publication Information
Clinical and Experimental Pediatrics / v.48, no.1, 2005 , pp. 34-39 More about this Journal
Abstract
Purpose : Perinatal complications associated with maternal smoking and alcohol ingestion in pregnancy have been well documented. But until now there has been no clinical data on it collected in our country. In this paper, we tried to research the association between maternal smoking and alcohol ingestion in pregnancy and the physical indices of the neonate at delivery among unmaried mothers from one charitable institution. Methods : We enlisted 125 unmarried with a history of smoking and alcohol consumption during pregnancy who delivered a baby in National Medical Center from March, 2001 to March, 2004 as a study group. As a control, 174 unmarried mothers without a history of smoking and alcohol were enlisted. Then, we compared the physical indices - birth weight, height, and the head circumference - of the neonates from both groups. Furthermore, we investigated the effects of the period and the quantity of maternal smoking and alcohol ingestion on the physical indices of the neonates from the both groups. Results : Low physical indices of neonates were found in the study group(either smoking group, or drinking group) compared with the control group. The quantity of smoking or drinking and the period of smoking or drinking have no significant effect on physical indices. Conclusion : We found that maternal smoking and alcohol result in the low physical index of neonates, and educational initiatives must be directed at expectant mothers to emphasize the harmful effects of smoking and alcohol ingestion in pregnancy.
Keywords
Smoking; Alcohol; Pregnancy; Neonate; Physical index;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Hwang SJ, Ou SW, Kim SN, Hwang HS, Cho BL, Huh BY. Smoking patterns and factors associated with smoking in Korean adult women. J Korean Acad Fam Med 2000;21:344-56
2 Andres RL, Day MC. Perinatal complications associated with maternal tobacco use. Semin Neonatol 2000;5:231-41   DOI   ScienceOn
3 Mulvihill JJ, Klimas JT, Stokes DC, Risemberg HM. Fetal alcohol syndrome : Seven new cases. Am J Obstet Gynecol 1976;125:937-41
4 Toschke AM, Koletzko B, Slikker W Jr., Hermann M, Kries R. Childhood obesity is associated with maternal smoking in pregnancy. Eur J Pediatr 2002;161:445-8   DOI   ScienceOn
5 Weissman MM, Warner V, Wickramaratne PJ, Kandel DB. Maternal smoking during pregnancy and psychopathology in offspring followed to adulthood. J Am Acad Child Adolesc Psychiatry 1999;38:892-9   DOI
6 Hinshaw S, Zupan B. Assessment of antisocial behavior in children and adolescents. Handbook of Antisocial Behavior. New York : Wiley & Sons Press, 1997:36-50
7 Kronick JB. Teratogenic effects of ethyl alcohol administered to pregnant mice. Am J Obstet Gynecol 1976;124: 676-80
8 Hanson JW, Jones KL, Smith DW. Fetal alcohol syndrome. JAMA 1976;235:1458-60   DOI   ScienceOn
9 Rice PA, Nesbitt REL, Cuenca VG, Zhang W, Gorden GB, Kim JJ. The effect of ethanol on the production of lactate, triglycerides, phospholipids, and free fatty acids in the perfused human placenta. Am J Obstet Gynecol 1986;155:207- 11
10 Palmer RH, Quellette EM, Warner L, Leichtman SR. Congenital malformations in offspring of a chronic alcoholic mother. Pediatrics 1974;53:490-4
11 England LJ, Kendrick JS, Wilson HG, Merritt RK, Gargiullo PM, Zahniser SC. Effects of smoking reduction during pregnancy on the birth weight of term infants. Am J Epidemiol 2001;154:694-701   DOI   ScienceOn
12 Lee JJ. The effects of maternal smoking in pregnancy. Korean J Perinatol 2002;13:357-65
13 Wisborg K, Kesmodel U, Henriksen TB, Olsen SF, Secher NJ. A prospective study of smoking during pregnancy and SIDS. Arch Dis Child 2000;83:203-6   DOI   ScienceOn
14 Tennes K, Blackkard C. Maternal Alcohol consumption, birth weight, and minor physical anomalies. Am J Obstet Gynecol 1980;138:774-80
15 Maloni JA. Preventing low weight. How smoking cessation counseling can help. AWHONN Lifelines 2001;5:32-5   DOI   ScienceOn
16 Cho TI, Na JY, Hong SK. Effect of an ethanol diet on various physiologic and neurologic parameters during pregnancy and on subsequent development. Korea Univ Med J 1987;24:75-84
17 Streissguth AP, Dwyer SL, Martin JC, Smith DW. Teratogenic effects of alcohol in humans and laboratory animals. Science 1980;209:353-61.   DOI   PUBMED
18 Jones KL, Smith DW, Ulleland CN, Streissguth AP. Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1973;2:1267-71