Browse > Article

Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older  

Park, Yong Won (Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital)
Han, Ji Whan (Department of Pediatrics, College of Medicine, Catholic University)
Park, In Sook (Department of Pediatrics, College of Medicine, University of Ulsan)
Kim, Chang Hwi (Department of Pediatrics, College of Medicine, Soonchunhyang University)
Cha, Sung Ho (Department of Pediatrics, College of Medicine, Kyunghee University)
Ma, Jae Sook (Department of Pediatrics, College of Medicine, Chonnam National University)
Kwon, Tae Chan (Department of Pediatrics, College of Medicine, Keimyung University)
Lee, Sang Bum (Department of Pediatrics, College of Medicine, Kyungpook National University)
Kim, Chul Ho (Department of Pediatrics, College of Medicine, Inje University, Seoul Paik Hospital)
Lee, Heung Jae (Department of Pediatrics, College of Medicine, Sungkyunkwan University)
Yun, Yong Soo (Department of Pediatrics, College of Medicine, Seoul National University)
Publication Information
Clinical and Experimental Pediatrics / v.48, no.10, 2005 , pp. 1139-1142 More about this Journal
Abstract
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of 211 KD patients 8 years of age and older were analyzed and compared with those of the KD patients less than 8 years of age. Results : 211 patients 8 years of age and older(1.3% of total KD patients) with the mean age of 9.8 years, included 142 cases aged 8-10 years, 42 cases aged 10-12 years, and 27 cases aged 12 years and older. The male-to-female ratio was 1.9 : 1, the recurrence rate was 3.8%, and the prevalence of cases in sibling was zero. Coronary arterial(CA) abnormalities were detected by echocardiography in 25.4% of the cases, including 7.6% of CA aneurysm cases. There was 1 case complicated by myocardial infarction. Conclusion : Comparing with the data of the KD patients less than 8 years of age, data of 211 patients 8 years of age and older showed significantly higher incidences of CA abnormalities(25.4% : 19.8%) and CA aneurysms(7.6% : 4.0%).
Keywords
Kawasaki disease; Mucocutaneous lymph node syndrome; Coronary aneurysm; Epide-miology; Child;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Park YW, Kim CH, Park IS, MA JS, Lee SB, Kim CH, et al. Epidemiologic study of Kawasaki disease in Korea, 1994-1996 : comparison of previous study in 1991-1993. J Korean Pediatr Soc 1999;42:1255-60
2 Tsuchida S, Yamanaka T, Tsuchida R, Nakamura Y, Yashiro M, Yanagawa H. Epidemiology of infant Kawasaki disease with a report of the youngest neonatal case ever reported in Japan. Acta Pediatr 1996;85:995-7   DOI   ScienceOn
3 Rozo JC, Jefferries JL, Eidem BW, Cook PJ. Kawasaki disease in the adult; a case report and review of the literature. Tex Heart Inst J 2004;31:160-4
4 Jackson JL, Kunkel MR, Libow L, Gates RH. Adult Kawasaki Disease. Arch Intern Med 1994;154:1398-405   DOI   ScienceOn
5 Newburger JW. Kawasaki disease : who is at risk. J Pediatr 2000;137:149-52   DOI   PUBMED   ScienceOn
6 Yun YS, Kim CH, Kim CH, Tockgo YC, Lee SK, Hong CY. Kawasaki disease in Korea. In : Kato H (ed). Kawasaki disease. Elsevier, New York, 1995;30-3
7 Suh YJ, Cho JW, Lee JH, Lee KS, Kim SS, Lee SK, et al. A case of Kawasaki disease in an adult. J Asthma Allergy Clin Immunol 2001;21:96-102
8 Melish ME. Kawasaki syndrome. Pediatrics Rev 1996;17:153-62   DOI   ScienceOn
9 Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Jpn J Allergy 1967;16:178-222
10 Nakano H, Ueda K, Saito A, Nojima K. Repeated quantitative angiograms in coronary arterial aneurysms in Kawasaki disease. Am J Cardiol 1985;56:846-51   DOI   ScienceOn
11 Rowley AH, Shulman ST. Kawasaki syndrome. Pediatr Clin North Am 1999;46:313-29   DOI   ScienceOn
12 Cho BK, Kwon SR, Yoon SJ, Chung MH, Lee SN, Lee SH. Adult-onset Kawasaki disease complicated by splenic infarction and coronary aneurysm. Korean J Infect Dis 2000;32:388-92
13 Stockheim JA, Innocentini N, Shulman ST. Kawasaki disease in older children and adolescents. J Pediatr 2000;137:250-2   DOI   ScienceOn
14 Newburger JW, Taubert KA, Shulman ST, Rowley AH, Gewitz MH, Takahashi M, et al. Summary and Abstracts of the Seventh International Kawasaki Disease Symposium : December 4-7, 2001, Hakone, Japan. Pediatr Res 2003;53:153-7
15 Park YW, Han JH, Park IS, Kim CH, Yun YS, Cha SH, et al. Epidemiologic picture of Kawasaki disease in Korea, 2000-2002. Pediatr Int 2005;47:382-7
16 Yanagawa H, Nakamura Y, Yashiro M, Oki I, Hirata S, Zhang T, et al. Incidence survey of Kawasaki disease in 1997 and 1998 in Japan. Pediatrics 2001;107:E33   DOI   ScienceOn
17 Park YW, Park IS, Kim CH, MA JS, Lee SB, Kim CH, et al. Epidemiologic study of Kawasaki disease in Korea, 1997-1999 : comparison of previous study in 1991-1996. J Korean Med Sci 2002;17:453-6
18 Momenah T, Sanatani S, Potts J, Sandor GG, Human DG, Patterson MW. Kawasaki disease in the older child. Pediatrics 1998;102:E7   DOI   ScienceOn
19 Research Committee on Kawasaki disease. Report of subcommittee on standardization of diagnostic criteria and reporting of coronary artery lesions in Kawasaki disease. Ministry of Health and Welfare, Tokyo, 1984
20 Sim CE, Park YW, Park IS, Kim CH, Yun YS. Clinical study of Kawasaki disease in infants 3 months of age and younger. J Korean Pediatr Cardiol 2003;7:102-5