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A Case of Hemophagocytic Lymphohistiocytosis in a Child with Systemic Lupus Erythematosus  

Hwang, Ja Young (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
No, Suk Man (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Jin (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Jang, Pil Sang (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Kim, Young Hoon (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Kim, Jin Tack (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Lee, Joon Sung (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
Publication Information
Clinical and Experimental Pediatrics / v.46, no.10, 2003 , pp. 1029-1031 More about this Journal
Abstract
Hemophagocytic lymphohistiocytosis is a reactive disorder characterized by a generalized non-malignant histiocytic proliferation with prominent hemophagocytosis by stimulated histiocytes in the bone marrow and reticuloendothelial systems resulting in pancytopenia and liver dysfunction. Several diseases including infection, malignancy and autoimmune disease are known to be causative disorders. This case demonstrated histiocytic hemophagocytosis in the bone marrow, resulting in pancytopenia during treatment of systemic lupus erythematosus and did not show any underlying disease.
Keywords
Hemophagocytic lymphohistiocytosis; Systemic lupus erythematosus;
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