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A Successful Transplant of HLA-3 Loci Mismatched Umbilical Cord Blood into a Patient with Acute Myeloid Leukemia from an Unrelated Donor  

Kwon, Byoung Chul (Department of Pediatrics, College of Medicine, Yonsei University)
Shin, Kyung Mi (Department of Pediatrics, College of Medicine, Yonsei University)
Won, Sung Chul (Department of Pediatrics, College of Medicine, Yonsei University)
Lyu, Chuhl Joo (Department of Pediatrics, College of Medicine, Yonsei University)
Yang, Chang Hyun (Department of Pediatrics, College of Medicine, Yonsei University)
Kim, Hyun Ok (Department of Clinical Pathology, College of Medicine, Yonsei University)
Publication Information
Clinical and Experimental Pediatrics / v.45, no.7, 2002 , pp. 912-916 More about this Journal
Abstract
Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15-month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than $500/mm^3$ occurred at day 49, and the platelet recovered greater than $20,000/mm^3$ independent of transfusion at day 81 after stem cell infusion.
Keywords
Cord blood transplantation; HLA-3 loci mismatching; Unrelated donor;
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