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A Case of Allergic Contact Dermatitis Due to Topical Minoxidil  

Kang, Kweon-Soo (Department of Dermatology, College of Medicine, Hallym University)
Lee, Bo-Hyun (Department of Dermatology, College of Medicine, Hallym University)
Han, Hee-Jin (Department of Dermatology, College of Medicine, Hallym University)
Park, Chun-Wook (Department of Dermatology, College of Medicine, Hallym University)
Lee, Cheol-Heon (Department of Dermatology, College of Medicine, Hallym University)
Publication Information
Korean journal of dermatology / v.42, no.4, 2004 , pp. 500-502 More about this Journal
Abstract
Minoxidil (2, 6-diamino-4-piperidinopyrimidine 1-oxide) is a systemic antihypertensive agent, the topical application of which has been shown to produce hair growth. Topical minoxidil solution (5% minoxidil, propylene glycol, alcohol, water) has generally been well-tolerated, but allergic contact dermatitis has been reported. When allergic contact dermatitis to minoxidil solution is suspected, evaluation of ingredients of minoxidil solution should be performed because allergic contact dermatitis due to propylene glycol in minoxidil solution has been frequently reported. A 34-year-old male presents with a diffuse erythematous patch on the scalp. He has applied minoxidil solution for 7 days due to androgenic alopecia. A Patch test with Korean standard series and the ingredients of used topical agents showed positive reactions to 1%, 2% and 5% minoxidil solution.
Keywords
Allergic contact dermatitis; Minoxidil;
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