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Sustained Release Properties of Vitamin C in Chitosan Molecular network  

Han Sang-Mun (Dept. of Environmental Health, Seoul Health College)
Publication Information
Journal of environmental and Sanitary engineering / v.20, no.2, 2005 , pp. 33-38 More about this Journal
Abstract
Chitosan is a dietary fiber because of a linear polysaccharide composed of $\beta-(1{\rightarrow}4)$-linked 2-amino-2-deoxy-D-glucopyranose. In this study, control release system of vitamin C has been estimated in chitosan molecular network as a vitamin C carrier of controlled release. The amount of released vitamin C were decreased in higher amount of chitosan concentration. Especially, vitamin C were slowly released from chitosan solution in dialysis membrane when compared with vitamin C solution alone in dialysis membrane. These result assumed that chitosan driving force is dependent on chitosan molecular weight and cationic property of amino group with anionic property of vitamin C.
Keywords
chitosan; vitamin C; drug control release device; chitosan molecular network;
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