Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BKCa activator LDD175 |
Wijerathne, Tharaka Darshana
(Laboratory of Physiology, College of Veterinary Medicine, Chungnam National University)
Kim, Jihyun (Laboratory of Physiology, College of Veterinary Medicine, Chungnam National University) Yang, Dongki (Department of Physiology, College of Medicine, Gachon University) Lee, Kyu Pil (Laboratory of Physiology, College of Veterinary Medicine, Chungnam National University) |
1 | Brenker C, Zhou Y, Muller A, Echeverry FA, Trotschel C, Poetsch A, Xia XM, Bonigk W, Lingle CJ, Kaupp UB, Strunker T. The -activated current of human sperm is mediated by Slo3. Elife. 2014;3:e01438. |
2 | Leonetti MD, Yuan P, Hsiung Y, Mackinnon R. Functional and structural analysis of the human SLO3 pH- and voltage-gated channel. Proc Natl Acad Sci U S A. 2012;109:19274-19279. DOI |
3 | Zeng XH, Yang C, Xia XM, Liu M, Lingle CJ. SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility. Proc Natl Acad Sci U S A. 2015;112:2599-2604. DOI |
4 | Clapham DE. Sperm BerserKers. Elife. 2013;2:e01469. |
5 | Okabe M. The cell biology of mammalian fertilization. Development. 2013;140:4471-4479. DOI |
6 | Tang QY, Zhang Z, Xia XM, Lingle CJ. Block of mouse Slo1 and Slo3 channels by CTX, IbTX, TEA, 4-AP and quinidine. Channels (Austin). 2010;4:22-41. DOI |
7 | Mansell SA, Publicover SJ, Barratt CL, Wilson SM. Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels. Mol Hum Reprod . 2014;20:392-408. DOI |
8 | Gribkoff VK, Lum-Ragan JT, Boissard CG, Post-Munson DJ, Meanwell NA, Starrett JE Jr, Kozlowski ES, Romine JL, Trojnacki JT, Mckay MC, Zhong J, Dworetzky SI. Effects of channel modulators on cloned large-conductance calcium-activated potassium channels. Mol Pharmacol . 1996;50:206-217. |
9 | Holland M, Langton PD, Standen NB, Boyle JP. Effects of the channel activator, NS1619, on rat cerebral artery smooth muscle. Br J Pharmacol. 1996;117:119-129. DOI |
10 | Bentzen BH, Nardi A, Calloe K, Madsen LS, Olesen SP, Grunnet M. The small molecule NS11021 is a potent and specific activator of -activated big-conductance channels. Mol Pharmacol. 2007;72:1033-1044. DOI |
11 | Gormemis AE, Ha TS, Im I, Jung KY, Lee JY, Park CS, Kim YC. Benzofuroindole analogues as potent BK(Ca) channel openers. Chembiochem. 2005;6:1745-1748. DOI |
12 | dela Pena IC, Yoon SY, Kim SM, Lee GS, Ryu JH, Park CS, Kim YC, Cheong JH. Bladder-relaxant properties of the novel benzofuroindole analogue LDD175. Pharmacology. 2009;83:367-378. DOI |
13 | Dela Pena IC, Yoon SY, Kim SM, Lee GS, Park CS, Kim YC, Cheong JH. Inhibition of intestinal motility by the putative BK(Ca) channel opener LDD175. Arch Pharm Res. 2009;32:413-420. DOI |
14 | Sung HH, Choo SH, Han DH, Chae MR, Kang SJ, Park CS, So I, Park JK, Lee SW. Effect of the novel channel opener LDD175 on the modulation of corporal smooth muscle tone. J Sex Med. 2015;12:29-38. DOI |
15 | Ha TS, Lim HH, Lee GE, Kim YC, Park CS. Electrophysiological characterization of benzofuroindole-induced potentiation of largeconductance -activated channels. Mol Pharmacol. 2006;69:1007-1014. |
16 | Lee BC, Lim HH, Kim S, Youn HS, Lee Y, Kim YC, Eom SH, Lee KW, Park CS. Localization of a site of action for benzofuroindoleinduced potentiation of channels. Mol Pharmacol. 2012;82:143-155. DOI |
17 | Kirichok Y, Navarro B, Clapham DE. Whole-cell patch-clamp measurements of spermatozoa reveal an alkaline-activated channel. Nature. 2006;439:737-740. DOI |
18 | Santi CM, Martinez-Lopez P, de la Vega-Beltran JL, Butler A, Alisio A, Darszon A, Salkoff L. The SLO3 sperm-specific potassium channel plays a vital role in male fertility. FEBS Lett. 2010;584:1041-1046. DOI |
19 | Zeng XH, Yang C, Kim ST, Lingle CJ, Xia XM. Deletion of the Slo3 gene abolishes alkalization-activated current in mouse spermatozoa. Proc Natl Acad Sci U S A. 2011;108:5879-5884. DOI |
20 | Yang C, Zeng XH, Zhou Y, Xia XM, Lingle CJ. LRRC52 (leucinerich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci U S A. 2011;108:19419-19424. DOI |
21 | Mannowetz N, Naidoo NM, Choo SA, Smith JF, Lishko PV. Slo1 is the principal potassium channel of human spermatozoa. Elife. 2013;2:e01009. |