Airway Smooth Muscle Sensitivity to Methacholine in Precision-Cut Lung Slices (PCLS) from Ovalbumin-induced Asthmatic Mice |
Kim, Hae Jin
(Department of Physiology, Seoul National University College of Medicine)
Kim, Yeryung (Department of Physiology, Seoul National University College of Medicine) Park, Su Jung (Department of Physiology, Seoul National University College of Medicine) Bae, Boram (Department of Internal Medicine, Seoul National University College of Medicine) Kang, Hye-Ryun (Department of Internal Medicine, Seoul National University College of Medicine) Cho, Sang-Heon (Department of Internal Medicine, Seoul National University College of Medicine) Yoo, Hae Young (Chung-Ang University Red Cross College of Nursing) Nam, Joo Hyun (Channelopathy Research Center (CRC), Dongguk University College of Medicine) Kim, Woo Kyung (Channelopathy Research Center (CRC), Dongguk University College of Medicine) Kim, Sung Joon (Department of Physiology, Seoul National University College of Medicine) |
1 | Sumino K, Sugar EA, Irvin CG, Kaminsky DA, Shade D, Wei CY, Holbrook JT, Wise RA, Castro M. American Lung Association Asthma Clinical Research Centers. Methacholine challenge test: diagnostic characteristics in asthmatic patients receiving controller medications. J Allergy Clin Immunol. 2012; 130:69-75.e6. DOI |
2 | Dixon C. The bronchial challenge test: a new direction in asthmatic management. J Natl Med Assoc. 1983;75:199-204. |
3 | Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunol Rev. 2004;202:175-190. DOI |
4 |
Matsumoto H, Hirata Y, Otsuka K, Iwata T, Inazumi A, Niimi A, Ito I, Ogawa E, Muro S, Sakai H, Chin K, Oku Y, Mishima M. Interleukin-13 enhanced |
5 | Kasaian MT, Miller DK. IL-13 as a therapeutic target for respiratory disease. Biochem Pharmacol. 2008;76:147-155. DOI |
6 | Shin YS, Takeda K, Gelfand EW. Understanding asthma using animal models. Allergy Asthma Immunol Res. 2009;1:10-18. DOI |
7 | Mullane K, Williams M. Animal models of asthma: reprise or reboot? Biochem Pharmacol. 2014;87:131-139. DOI |
8 | Held HD, Martin C, Uhlig S. Characterization of airway and vascular responses in murine lungs. Br J Pharmacol. 1999;126: 1191-1199. DOI |
9 | Blacquiere MJ, Hylkema MN, Postma DS, Geerlings M, Timens W, Melgert BN. Airway inflammation and remodeling in two mouse models of asthma: comparison of males and females. Int Arch Allergy Immunol. 2010;153:173-181. DOI |
10 | Park SJ, Yoo HY, Kim HJ, Kim JK, Zhang YH, Kim SJ. Requirement of pretone by thromboxane A(2) for hypoxic pulmonary vasoconstriction in precision-cut lung slices of rat. Korean J Physiol Pharmacol. 2012;16:59-64. DOI |
11 | Martin C, Uhlig S, Ullrich V. Videomicroscopy of methacholineinduced contraction of individual airways in precision-cut lung slices. Eur Respir J. 1996;9:2479-2487. DOI |
12 | Henjakovic M, Martin C, Hoymann HG, Sewald K, Ressmeyer AR, Dassow C, Pohlmann G, Krug N, Uhlig S, Braun A. Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies. Toxicol Sci. 2008;106: 444-453. DOI |
13 | Chew AD, Hirota JA, Ellis R, Wattie J, Inman MD, Janssen LJ. Effects of allergen on airway narrowing dynamics as assessed by lung-slice technique. Eur Respir J. 2008;31:532-538. DOI |
14 | Kim YK, Oh SY, Jeon SG, Park HW, Lee SY, Chun EY, Bang B, Lee HS, Oh MH, Kim YS, Kim JH, Gho YS, Cho SH, Min KU, Kim YY, Zhu Z. Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma. J Immunol. 2007;178:5375-5382. DOI |
15 | Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med. 1997;156:766-775. DOI |
16 | Erle DJ, Sheppard D. The cell biology of asthma. J Cell Biol. 2014;205:621-631. DOI |
17 | Gosling M, Poll C, Li S. TRP channels in airway smooth muscle as therapeutic targets. Naunyn Schmiedebergs Arch Pharmacol. 2005;371:277-284. DOI |
18 |
Gao YD, Zou JJ, Zheng JW, Shang M, Chen X, Geng S, Yang J. Promoting effects of IL-13 on |
19 |
Gao YD, Zheng JW, Li P, Cheng M, Yang J. Store-operated |
20 | Ressmeyer AR, Larsson AK, Vollmer E, Dahlen SE, Uhlig S, Martin C. Characterisation of guinea pig precision-cut lung slices: comparison with human tissues. Eur Respir J. 2006;28: 603-611. DOI |
21 | Jung YJ, Suh EC, Lee KE. Oxygen/Glucose Deprivation and Reperfusion Cause Modifications of Postsynaptic Morphology and Activity in the CA3 Area of Organotypic Hippocampal Slice Cultures. Korean J Physiol Pharmacol. 2012;16:423-429. DOI |
22 | Wohlsen A, Martin C, Vollmer E, Branscheid D, Magnussen H, Becker WM, Lepp U, Uhlig S. The early allergic response in small airways of human precision-cut lung slices. Eur Respir J. 2003;21:1024-1032. DOI |
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