Altered Regulation of Renal Acid Base Transporters in Response to Ammonium Chloride Loading in Rats
![]() ![]() |
Kim, Eun-Young
(Department of Physiology, Chonnam National University Medical School)
Choi, Joon-Seok (Department of Physiology, Chonnam National University Medical School) Lee, Ko-Eun (Department of Physiology, Chonnam National University Medical School) Kim, Chang-Seong (Department of Physiology, Chonnam National University Medical School) Bae, Eun-Hui (Department of Physiology, Chonnam National University Medical School) Ma, Seong-Kwon (Department of Physiology, Chonnam National University Medical School) Kim, Suhn-Hee (Department of Internal Medicine, Chonnam National University Medical School) Lee, Jong-Un (Department of Physiology, Chonnam National University Medical School) Kim, Soo-Wan (Department of Physiology, Chonnam National University Medical School) |
1 | Tizianello A, Deferrari G, Garibotto G, Robaudo C, Acquarone N, Ghiggeri GM. Renal ammoniagenesis in an early stage of metabolic acidosis in man. J Clin Invest. 1982;69:240-250. DOI |
2 | Nowik M, Picard N, Stange G, Capuano P, Tenenhouse HS, Biber J, Murer H, Wagner CA. Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption. Pflugers Arch. 2008;457:539-549. DOI ScienceOn |
3 | Goldstein L, Boylan JM, Schrock H. Adaptation of renal ammonia production in the diabetic ketoacidotic rat. Kidney Int. 1980;17:57-65. DOI ScienceOn |
4 | Kim GH, Martin SW, Fernandez-Llama P, Masilamani S, Packer RK, Knepper MA. Long-term regulation of renal Nadependent cotransporters and ENaC: response to altered acidbase intake. Am J Physiol Renal Physiol. 2000;279:F459-467. DOI |
5 | Bae EH, Kim IJ, Ma SK, Lee JU, Kim SW. Altered regulation of renal nitric oxide and atrial natriuretic peptide systems in lipopolysaccharide-induced kidney injury. Korean J Physiol Pharmacol. 2011;15:273-277. DOI ScienceOn |
6 | Aruga S, Wehrli S, Kaissling B, Moe OW, Preisig PA, Pajor AM, Alpern RJ. Chronic metabolic acidosis increases NaDC-1 mRNA and protein abundance in rat kidney. Kidney Int. 2000;58:206-215. DOI ScienceOn |
7 | Hafner P, Grimaldi R, Capuano P, Capasso G, Wagner CA. Pendrin in the mouse kidney is primarily regulated by Clexcretion but also by systemic metabolic acidosis. Am J Physiol Cell Physiol. 2008;295:C1658-1667. DOI ScienceOn |
8 | Nowik M, Lecca MR, Velic A, Rehrauer H, Brandli AW, Wagner CA. Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis. Physiol Genomics. 2008;32:322-334. DOI |
9 |
Bobulescu IA, Moe OW. |
10 | Wagner CA, Devuyst O, Bourgeois S, Mohebbi N. Regulated acid-base transport in the collecting duct. Pflugers Arch. 2009;458:137-156. DOI ScienceOn |
11 |
Romero MF, Boron WF. Electrogenic |
12 | Orlowski J, Kandasamy RA, Shull GE. Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. J Biol Chem. 1992;267:9331-9339. |
13 |
Tse CM, Brant SR, Walker MS, Pouyssegur J, Donowitz M. Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific |
14 | Ambuhl PM, Amemiya M, Danczkay M, Lotscher M, Kaissling B, Moe OW, Preisig PA, Alpern RJ. Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney. Am J Physiol. 1996;271:F917-925. |
15 |
Burnham CE, Flagella M, Wang Z, Amlal H, Shull GE, Soleimani M. Cloning, renal distribution, and regulation of the rat |
16 |
Gross E, Hopfer U. Activity and stoichiometry of |
17 | Kwon TH, Fulton C, Wang W, Kurtz I, Frokiaer J, Aalkjaer C, Nielsen S. Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1. Am J Physiol Renal Physiol. 2002;282:F341-351. DOI |
18 | Huber S, Asan E, Jons T, Kerscher C, Puschel B, Drenckhahn D. Expression of rat kidney anion exchanger 1 in type A intercalated cells in metabolic acidosis and alkalosis. Am J Physiol. 1999;277:F841-849. |
19 | Purkerson JM, Tsuruoka S, Suter DZ, Nakamori A, Schwartz GJ. Adaptation to metabolic acidosis and its recovery are associated with changes in anion exchanger distribution and expression in the cortical collecting duct. Kidney Int. 2010;78:993-1005. DOI ScienceOn |
20 | Ambuhl PM, Zajicek HK, Wang H, Puttaparthi K, Levi M. Regulation of renal phosphate transport by acute and chronic metabolic acidosis in the rat. Kidney Int. 1998;53:1288-1298. DOI ScienceOn |
21 | Welsh-Bacic D, Nowik M, Kaissling B, Wagner CA. Proliferation of acid-secretory cells in the kidney during adaptive remodelling of the collecting duct. PLoS One. 2011;6:e25240. DOI |
22 | Cheval L, Morla L, Elalouf JM, Doucet A. Kidney collecting duct acid-base "regulon". Physiol Genomics. 2006;27:271-281. DOI ScienceOn |
23 | Curthoys NP, Gstraunthaler G. Mechanism of increased renal gene expression during metabolic acidosis. Am J Physiol Renal Physiol. 2001;281:F381-390. DOI |
24 |
Biemesderfer D, Pizzonia J, Abu-Alfa A, Exner M, Reilly R, Igarashi P, Aronson PS. NHE3: a |
25 | Yoshitomi K, Burckhardt BC, Fromter E. Rheogenic sodiumbicarbonate cotransport in the peritubular cell membrane of rat renal proximal tubule. Pflugers Arch. 1985;405:360-366. DOI ScienceOn |
26 |
Alper SL, Natale J, Gluck S, Lodish HF, Brown D. Subtypes of intercalated cells in rat kidney collecting duct defined by antibodies against erythroid band 3 and renal vacuolar |
27 | Wall SM. Recent advances in our understanding of intercalated cells. Curr Opin Nephrol Hypertens. 2005;14:480-484. DOI ScienceOn |
28 | Kim YH, Kwon TH, Frische S, Kim J, Tisher CC, Madsen KM, Nielsen S. Immunocytochemical localization of pendrin in intercalated cell subtypes in rat and mouse kidney. Am J Physiol Renal Physiol. 2002;283:F744-754. DOI ScienceOn |
![]() |