4-phenylbutyric Acid Regulates Collagen Synthesis and Secretion Induced by High Concentrations of Glucose in Human Gingival Fibroblasts |
Lee, Geum-Hwa
(Department of Dental Pharmacology and Wonkwang Dental Research Institute, School of Dentistry, Wonkwang University)
Oh, Hyo-Won (Department of Public Oral Health and Preventive Dentistry, School of Dentistry, Wonkwang University) Lim, Hyun-Dae (Department of Oral Medicine and Diagnosis, School of Dentistry, Wonkwang University) Lee, Wan (Department of Oral and Maxillofacial Radiology, School of Dentistry, Wonkwang University) Chae, Han-Jung (Department of Pharmacology and Institute of Cardiovascular Research, Medical School, Chonbuk National University) Kim, Hyung-Ryong (Department of Dental Pharmacology and Wonkwang Dental Research Institute, School of Dentistry, Wonkwang University) |
1 | Qi X, Hosoi T, Okuma Y, Kaneko M, Nomura Y. Sodium 4-phenylbutyrate protects against cerebral ischemic injury. Mol Pharmacol. 2004;66:899-908. DOI ScienceOn |
2 | Rubenstein RC, Zeitlin PL. Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of DeltaF508-CFTR. Am J Physiol Cell Physiol. 2000;278:C259-267. |
3 | Lee GH, Yan C, Shin SJ, Hong SC, Ahn T, Moon A, Park SJ, Lee YC, Yoo WH, Kim HT, Kim DS, Chae SW, Kim HR, Chae HJ. BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function. Oncogene. 2010;29:2130-2141. DOI ScienceOn |
4 | Kim ES, Kim JS, Kim SG, Hwang S, Lee CH, Moon A. Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-Gq coupling. J Cell Sci. 2011;124:2220-2230. DOI |
5 | Del Prete D, Anglani F, Forino M, Ceol M, Fioretto P, Nosadini R, Baggio B, Gambaro G. Down-regulation of glomerular matrix metalloproteinase-2 gene in human NIDDM. Diabetologia. 1997;40:1449-1454. DOI ScienceOn |
6 | McLennan SV, Kelly DJ, Cox AJ, Cao Z, Lyons JG, Yue DK, Gilbert RE. Decreased matrix degradation in diabetic nephropathy: effects of ACE inhibition on the expression and activities of matrix metalloproteinases. Diabetologia. 2002;45:268-275. DOI ScienceOn |
7 | Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature. 1999;397:271-274. DOI ScienceOn |
8 | Vattem KM, Wek RC. Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA. 2004;101:11269-11274. DOI ScienceOn |
9 | Shi Y, Vattem KM, Sood R, An J, Liang J, Stramm L, Wek RC. Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol. 1998;18:7499-7509. |
10 | Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell. 2000;5:897-904. DOI ScienceOn |
11 | Yoshizawa T, Hinoi E, Jung DY, Kajimura D, Ferron M, Seo J, Graff JM, Kim JK, Karsenty G. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. J Clin Invest. 2009;119:2807-2817. DOI ScienceOn |
12 | Disthabanchong S, Radinahamed P, Stitchantrakul W, Hongeng S, Rajatanavin R. Chronic metabolic acidosis alters osteoblast differentiation from human mesenchymal stem cells. Kidney Int. 2007;71:201-209. DOI ScienceOn |
13 | Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Gorgun CZ, Hotamisligil GS. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006;313:1137-1140. DOI ScienceOn |
14 | Welch WJ, Brown CR. Influence of molecular and chemical chaperones on protein folding. Cell Stress Chaperones. 1996;1:109-115. DOI ScienceOn |
15 | Kajimura K, Takagi Y, Ueba N, Yamasaki K, Sakagami Y, Yokoyama H, Yoneda K. Protective effect of Astragali Radix by intraperitoneal injection against Japanese encephalitis virus infection in mice. Biol Pharm Bull. 1996;19:855-859. DOI ScienceOn |
16 | Zhao JH, Liu HL, Lin HY, Huang CH, Fang HW, Chen SS, Ho Y, Tsai WB, Chen WY. Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases. Perspect Medicin Chem. 2007;1:39-48. |
17 | Rieusset J. Mitochondria and endoplasmic reticulum: mitochondria- endoplasmic reticulum interplay in type 2 diabetes pathophysiology. Int J Biochem Cell Biol. 2011;43:1257-1262. DOI ScienceOn |
18 | Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Gorgun CZ, Hotamisligil GS. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006;313:1137-1140. DOI ScienceOn |
19 | Rubenstein RC, Egan ME, Zeitlin PL. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR. J Clin Invest. 1997;100:2457-2465. DOI ScienceOn |
20 | Tanaka T, Tomaru Y, Nomura Y, Miura H, Suzuki M, Hayashizaki Y. Comprehensive search for HNF-1beta-regulated genes in mouse hepatoma cells perturbed by transcription regulatory factor-targeted RNAi. Nucleic Acids Res. 2004;32:2740-2750. DOI |
21 | Roque T, Boncoeur E, Saint-Criq V, Bonvin E, Clement A, Tabary O, Jacquot J. Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling. J Pharmacol Exp Ther. 2008;326:949-956. DOI |
22 | Adler S. Structure-function relationships associated with extracellular matrix alterations in diabetic glomerulopathy. J Am Soc Nephrol. 1994;5:1165-1172. |
23 | Kumano K, Schiller B, Hjelle JT, Moran J. Effects of osmotic solutes on fibronectin mRNA expression in rat peritoneal mesothelial cells. Blood Purif. 1996;14:165-169. DOI ScienceOn |
24 | Silva JA, Lorencini M, Reis JR, Carvalho HF, Cagnon VH, Stach-Machado DR. The influence of type I diabetes mellitus in periodontal disease induced changes of the gingival epithelium and connective tissue. Tissue Cell. 2008;40:283-292. DOI ScienceOn |
25 | Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007;8:519-529. DOI ScienceOn |
26 | Taylor GW. Bidirectional interrelationships between diabetes and periodontal diseases: an epidemiologic perspective. Ann Periodontol. 2001;6:99-112. DOI ScienceOn |
27 | Seo HY, Kim YD, Lee KM, Min AK, Kim MK, Kim HS, Won KC, Park JY, Lee KU, Choi HS, Park KG, Lee IK. Endoplasmic reticulum stress-induced activation of activating transcription factor 6 decreases insulin gene expression via up-regulation of orphan nuclear receptor small heterodimer partner. Endocrinology. 2008;149:3832-3841. DOI ScienceOn |
28 | Lipson KL, Fonseca SG, Ishigaki S, Nguyen LX, Foss E, Bortell R, Rossini AA, Urano F. Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab. 2006;4:245-254. DOI ScienceOn |
29 | Zhang L, Lai E, Teodoro T, Volchuk A. GRP78, but not protein-disulfide isomerase, partially reverses hyperglycemia-induced inhibition of insulin synthesis and secretion in pancreatic {beta}-cells. J Biol Chem. 2009;284:5289-5298. |
30 | Lee HB, Ha H. Experimental approaches to diabetic nephropathy. Kidney Int. 1997;52(Suppl 60):S1-S2. |
31 | Perfumo F, Altieri P, Degl'Innocenti ML, Ghiggeri GM, Caridi G, Trivelli A, Gusmano R. Effects of peritoneal effluents on mesothelial cells in culture: cell proliferation and extracellular matrix regulation. Nephrol Dial Transplant. 1996;11:1803-1809. DOI ScienceOn |
32 | Poitout V, Hagman D, Stein R, Artner I, Robertson RP, Harmon JS. Regulation of the insulin gene by glucose and fatty acids. J Nutr. 2006;136:873-876. |
33 | Melloul D, Marshak S, Cerasi E. Regulation of insulin gene transcription. Diabetologia. 2002;45:309-326. DOI ScienceOn |