Regulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic Mice |
Jang, Cho-Rong
(Department of Pharmacology, College of Medicine, The Catholic University of Korea)
Lim, Ji-Hee (Depratment of Internal Medicine, College of Medicine, The Catholic University of Korea) Park, Cheol-Whee (Depratment of Internal Medicine, College of Medicine, The Catholic University of Korea) Cho, Young-Jin (Department of Pharmacology, College of Medicine, The Catholic University of Korea) |
1 | Ke H, Huai Q. Structures of calcineurin and its complexes with immunophilins-immunosuppressants. Biochem Biophys Res Commun. 2003;311:1095-1102. DOI ScienceOn |
2 | Cho YJ, Abe M, Kim SY, Sato Y. Raf-1 is a binding partner of DSCR1. Arch Biochem Biophys. 2005;439:121-128. DOI ScienceOn |
3 | Lee EJ, Seo SR, Um JW, Park J, Oh Y, Chung KC. NFkappaB- inducing kinase phosphorylates and blocks the degradation of Down syndrome candidate region 1. J Biol Chem. 2008;283:3392-3400. DOI |
4 | Asada S, Ikeda A, Nagao R, Hama H, Sudo T, Fukamizu A, Kasuya Y, Kishi T. Oxidative stress-induced ubiquitination of RCAN1 mediated by SCFbeta-TrCP ubiquitin ligase. Int J Mol Med. 2008;22:95-104. |
5 | Lee JY, Lee HJ, Lee EJ, Jang SH, Kim H, Yoon JH, Chung KC. Down syndrome candidate region-1 protein interacts with Tollip and positively modulates interleukin-1 receptor-mediated signaling. Biochim Biophys Acta. 2009;1790:1673-1680. DOI ScienceOn |
6 | Lee HJ, Kim YS, Sato Y, Cho YJ. RCAN1-4 knockdown attenuates cell growth through the inhibition of Ras signaling. FEBS Lett. 2009;583:2557-2564. DOI ScienceOn |
7 | Bradshaw AD, Francki A, Motamed K, Howe C, Sage EH. Primary mesenchymal cells isolated from SPARC-null mice exhibit altered morphology and rates of proliferation. Mol Biol Cell. 1999;10:1569-1579. DOI |
8 | Kim YS, Cho KO, Lee HJ, Kim SY, Sato Y, Cho YJ. Down syndrome candidate region 1 increases the stability of the IkappaBalpha protein: implications for its anti-inflammatory effects. J Biol Chem. 2006;281:39051-39061. DOI |
9 | Kim YS, Lee HJ, Jang C, Kim HS, Cho YJ. Knockdown of RCAN1.4 increases susceptibility to FAS-mediated and DNAdamage- induced apoptosis by upregulation of p53 expression. Korean J Physiol Pharmacol. 2009;13:483-489. DOI |
10 | Hummel KP, Dickie MM, Coleman DL. Diabetes, a new mutation in the mouse. Science. 1966;153:1127-1128. DOI ScienceOn |
11 | Yang J, Rothermel B, Vega RB, Frey N, McKinsey TA, Olson EN, Bassel-Duby R, Williams RS. Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. Circ Res. 2000;87:E61-68. DOI |
12 | David KC, Scott RH, Nixon GF. Advanced glycation endproducts induce a proliferative response in vascular smooth muscle cells via altered calcium signaling. Biochem Pharmacol. 2008; 76:1110-1120. DOI ScienceOn |
13 | Minami T, Horiuchi K, Miura M, Abid MR, Takabe W, Noguchi N, Kohro T, Ge X, Aburatani H, Hamakubo T, Kodama T, Aird WC. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. J Biol Chem. 2004;279:50537-50554. DOI |
14 | Simon M, Rockl W, Hornig C, Grone EF, Theis H, Weich HA, Fuchs E, Yayon A, Grone HJ. Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [125I]VEGF binding sites. J Am Soc Nephrol. 1998;9:1032-1044. |
15 | Cooper ME, Vranes D, Youssef S, Stacker SA, Cox AJ, Rizkalla B, Casley DJ, Bach LA, Kelly DJ, Gilbert RE. Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes. Diabetes. 1999;48:2229-2239. DOI ScienceOn |
16 | Wang P, Heitman J. The cyclophilins. Genome Biol. 2005;6:226. DOI |
17 | Gooch JL, Gorin Y, Zhang BX, Abboud HE. Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation. J Biol Chem. 2004;279:15561-15570. DOI |
18 | Mehta S, Li H, Hogan PG, Cunningham KW. Domain architecture of the regulators of calcineurin (RCANs) and identification of a divergent RCAN in yeast. Mol Cell Biol. 2009;29:2777-2793. DOI ScienceOn |
19 | Gooch JL, Barnes JL, Garcia S, Abboud HE. Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation. Am J Physiol Renal Physiol. 2003;284:F144-154. DOI |
20 | Gooch JL, Tang Y, Ricono JM, Abboud HE. Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurindependent mechanism. J Biol Chem. 2001;276:42492-42500. DOI |
21 | Rothermel BA, Vega RB, Williams RS. The role of modulatory calcineurin-interacting proteins in calcineurin signaling. Trends Cardiovasc Med. 2003;13:15-21. DOI ScienceOn |
22 | Fuentes JJ, Genesca L, Kingsbury TJ, Cunningham KW, Perez-Riba M, Estivill X, de la Luna S. DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways. Hum Mol Genet. 2000;9:1681-1690. DOI |
23 | Fuentes JJ, Pritchard MA, Planas AM, Bosch A, Ferrer I, Estivill X. A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart. Hum Mol Genet. 1995;4:1935-1944. DOI ScienceOn |
24 | Fuentes JJ, Pritchard MA, Estivill X. Genomic organization, alternative splicing, and expression patterns of the DSCR1 (Down syndrome candidate region 1) gene. Genomics. 1997;44: 358-361. DOI ScienceOn |
25 | Abe M, Sato Y. cDNA microarray analysis of the gene expression profile of VEGF-activated human umbilical vein endothelial cells. Angiogenesis. 2001;4:289-298. DOI ScienceOn |
26 | Mann KM, Ray JL, Moon ES, Sass KM, Benson MR. Calcineurin initiates smooth muscle differentiation in neural crest stem cells. J Cell Biol. 2004;165:483-491.25. DOI ScienceOn |
27 | Cho KO, Kim YS, Cho YJ, Kim SY. Upregulation of DSCR1 (RCAN1 or Adapt78) in the peri-infarct cortex after experimental stroke. Exp Neurol. 2008;212:85-92. DOI ScienceOn |
28 | Iidaka K, McCoy J, Kimmelstiel P. The glomerular mesangium: a quantitative analy-sis. Lab Invest. 1968;19:573-579. |
29 | Crawford DR, Leahy KP, Abramova N, Lan L, Wang Y, Davies KJ. Hamster adapt78 mRNA is a Down syndrome critical region homologue that is inducible by oxidative stress. Arch Biochem Biophys. 1997;342:6-12. DOI ScienceOn |
30 | Luo JD, Wang YY, Fu WL, Wu J, Chen AF. Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice. Circulation. 2004;110:2484-2493. DOI ScienceOn |
31 | Kawano K, Arakawa M, McCoy J, Porch J, Kimmelstiel P. Quantitative study of glomeruli. Focal glomerulonephritis and diabetic glomerulosclerosis. Lab Invest. 1969;21:269-275. |
32 | Ayo SH, Radnik RA, Garoni JA, Glass WF 2nd, Kreisberg JI. High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol. 1990;136: 1339-1348. |
33 | Doi T, Vlassara H, Kirstein M, Yamada Y, Striker GE, Striker LJ. Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor. Proc Natl Acad Sci USA. 1992;89:2873-2877. DOI ScienceOn |
34 | Mason RM, Wahab NA. Extracellular matrix metabolism in diabetic nephropathy. J Am Soc Nephrol. 2003;14:1358-1373. DOI ScienceOn |
35 | Flyvbjerg A. Putative pathophysiological role of growth factors and cytokines in experimental diabetic kidney disease. Diabetologia. 2000;43:1205-1223. DOI ScienceOn |
36 | Seo SR, Chung KC. CREB activates proteasomal degradation of DSCR1/RCAN1. FEBS Lett. 2008;582:1889-1893. DOI ScienceOn |
37 | Chiarelli F, Gaspari S, Marcovecchio ML. Role of growth factors in diabetic kidney disease. Horm Metab Res. 2009;41:585-593. DOI ScienceOn |
38 | Blazquez-Medela AM, Lopez-Novoa JM, Martinez-Salgado C. Mechanisms involved in the genesis of diabetic nephropathy. Curr Diabetes Rev. 2010;6:68-87. DOI ScienceOn |
39 | Grønbaek H, Volmers P, Bjørn SF, Osterby R, Orskov H, Flyvbjerg A. Effect of GH/IGF-I deficiency on long-term renal changes and urinary albumin excretion in diabetic dwarf rats. Am J Physiol. 1997;272:E918-924. |